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多系统萎缩合并梅杰综合征:一例罕见病例报告。

Multiple system atrophy associated with Meige syndrome: A rare case report.

作者信息

Liang Jiaji, He Xi, Lu Jinqiang

机构信息

Department of Plastic Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, China.

出版信息

Radiol Case Rep. 2023 Jun 29;18(9):3192-3195. doi: 10.1016/j.radcr.2023.04.055. eCollection 2023 Sep.

DOI:10.1016/j.radcr.2023.04.055
PMID:37448600
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10338191/
Abstract

Multiple system atrophy (MSA) is a rare form of adult-onset α-synucleinopathy. Meige syndrome, identified as bilateral blepharospasm and oromandibular dystonia, is a type of focal dystonic movement disorder. This case report aims to highlight the clinical features of multiple system atrophy associated with Meige syndrome in a patient. Additionally, we aim to provide the treatment experience in a patient with Meige syndrome as this is an extremely rare clinical case.

摘要

多系统萎缩(MSA)是一种罕见的成人起病的α-突触核蛋白病。Meige综合征被定义为双侧眼睑痉挛和口下颌肌张力障碍,是一种局灶性肌张力障碍性运动障碍。本病例报告旨在突出一名多系统萎缩合并Meige综合征患者的临床特征。此外,鉴于这是一个极其罕见的临床病例,我们旨在分享该Meige综合征患者的治疗经验。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/107e/10338191/d15d578448c2/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/107e/10338191/d15d578448c2/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/107e/10338191/d15d578448c2/gr1.jpg

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本文引用的文献

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Current Management and Emerging Therapies in Multiple System Atrophy.多种系统萎缩的当前治疗和新兴疗法。
Neurotherapeutics. 2020 Oct;17(4):1582-1602. doi: 10.1007/s13311-020-00890-x.
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Intrathecal administration of autologous mesenchymal stem cells in multiple system atrophy.鞘内注射自体间充质干细胞治疗多系统萎缩。
Neurology. 2019 Jul 2;93(1):e77-e87. doi: 10.1212/WNL.0000000000007720. Epub 2019 May 31.
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Meige's syndrome: History, epidemiology, clinical features, pathogenesis and treatment.梅杰综合征:历史、流行病学、临床特征、发病机制与治疗
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Outcome of deep brain stimulation in slowly progressive multiple system atrophy: A clinico-pathological series and review of the literature.
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