• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Calcium handling: a strategy to fight neurodegeneration in Alzheimer's disease.

作者信息

La Barbera Livia, Spoleti Elena, D'Amelio Marcello

机构信息

Department of Sciences and Technologies for Humans and Environment, Università Campus Bio- Medico di Roma; Department of Experimental Neurosciences, IRCCS Santa Lucia Foundation, Rome, Italy.

Department of Sciences and Technologies for Humans and Environment, Università Campus Bio-Medico di Roma, Rome, Italy.

出版信息

Neural Regen Res. 2023 Dec;18(12):2685-2686. doi: 10.4103/1673-5374.374004.

DOI:10.4103/1673-5374.374004
PMID:37449622
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10358684/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4eaf/10358684/a2da176f0438/NRR-18-2685-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4eaf/10358684/a2da176f0438/NRR-18-2685-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4eaf/10358684/a2da176f0438/NRR-18-2685-g001.jpg

相似文献

1
Calcium handling: a strategy to fight neurodegeneration in Alzheimer's disease.钙处理：对抗阿尔茨海默病神经退行性变的一种策略。
Neural Regen Res. 2023 Dec;18(12):2685-2686. doi: 10.4103/1673-5374.374004.
2
EEG evidence of compensatory mechanisms in preclinical Alzheimer's disease.临床前阿尔茨海默病中补偿机制的脑电图证据。
Brain. 2019 Jul 1;142(7):2096-2112. doi: 10.1093/brain/awz150.
3
Subjective cognitive decline: opposite links to neurodegeneration across the Alzheimer's continuum.主观认知衰退：在阿尔茨海默病连续体中与神经退行性变的相反联系。
Brain Commun. 2021 Sep 1;3(3):fcab199. doi: 10.1093/braincomms/fcab199. eCollection 2021.
4
Clinical and cognitive trajectories in cognitively healthy elderly individuals with suspected non-Alzheimer's disease pathophysiology (SNAP) or Alzheimer's disease pathology: a longitudinal study.认知健康的老年疑似非阿尔茨海默病病理生理学 (SNAP) 或阿尔茨海默病病理个体的临床和认知轨迹：一项纵向研究。
Lancet Neurol. 2016 Sep;15(10):1044-53. doi: 10.1016/S1474-4422(16)30125-9. Epub 2016 Jul 20.
5
Serial PIB and MRI in normal, mild cognitive impairment and Alzheimer's disease: implications for sequence of pathological events in Alzheimer's disease.正常、轻度认知障碍和阿尔茨海默病患者的连续淀粉样蛋白成像和磁共振成像：对阿尔茨海默病病理事件顺序的启示
Brain. 2009 May;132(Pt 5):1355-65. doi: 10.1093/brain/awp062. Epub 2009 Mar 31.
6
Dysregulated Ca Homeostasis as a Central Theme in Neurodegeneration: Lessons from Alzheimer's Disease and Wolfram Syndrome.钙稳态失调作为神经退行性变的核心主题：来自阿尔茨海默病和 WOLFRAM 综合征的启示。
Cells. 2022 Jun 18;11(12):1963. doi: 10.3390/cells11121963.
7
Excitotoxicity, calcium and mitochondria: a triad in synaptic neurodegeneration.兴奋毒性、钙离子和线粒体：突触神经退行性变的三联体。
Transl Neurodegener. 2022 Jan 25;11(1):3. doi: 10.1186/s40035-021-00278-7.
8
STIM1 deficiency is linked to Alzheimer's disease and triggers cell death in SH-SY5Y cells by upregulation of L-type voltage-operated Ca entry.钙库操纵性钙通道蛋白 1 （stromal interaction molecule 1，STIM1）缺失与阿尔茨海默病相关，通过上调 L 型电压门控钙通道增加细胞内钙离子浓度，进而触发 SH-SY5Y 细胞死亡。
J Mol Med (Berl). 2018 Oct;96(10):1061-1079. doi: 10.1007/s00109-018-1677-y. Epub 2018 Aug 7.
9
Brain Ischemia as a Prelude to Alzheimer's Disease.脑缺血——阿尔茨海默病的前奏
Front Aging Neurosci. 2021 Feb 18;13:636653. doi: 10.3389/fnagi.2021.636653. eCollection 2021.
10
Genes Associated with Alzheimer’s Disease in Post-Ischemic Brain Neurodegeneration与缺血后脑神经退行性变中阿尔茨海默病相关的基因

引用本文的文献

1
Therapeutic potential of melatonin-induced mitophagy in the pathogenesis of Alzheimer's disease.褪黑素诱导的线粒体自噬在阿尔茨海默病发病机制中的治疗潜力
Inflammopharmacology. 2025 Jul 22. doi: 10.1007/s10787-025-01859-y.

本文引用的文献

1
Upregulation of Ca-binding proteins contributes to VTA dopamine neuron survival in the early phases of Alzheimer's disease in Tg2576 mice.钙结合蛋白的上调有助于 Tg2576 小鼠阿尔茨海默病早期阶段中 VTA 多巴胺神经元的存活。
Mol Neurodegener. 2022 Nov 25;17(1):76. doi: 10.1186/s13024-022-00580-6.
2
In vivo human molecular neuroimaging of dopaminergic vulnerability along the Alzheimer's disease phases.在阿尔茨海默病各阶段对多巴胺能易损性进行的活体人类分子神经影像学研究。
Alzheimers Res Ther. 2021 Nov 12;13(1):187. doi: 10.1186/s13195-021-00925-1.
3
Re-Analysis of the STEADY-PD II Trial-Evidence for Slowing the Progression of Parkinson's Disease.
STEADY-PD II 试验再分析——帕金森病进展减缓的证据。
Mov Disord. 2022 Feb;37(2):334-342. doi: 10.1002/mds.28850. Epub 2021 Nov 12.
4
Dopaminergic dysfunction in the 3xTg-AD mice model of Alzheimer's disease.阿尔茨海默病 3xTg-AD 小鼠模型中的多巴胺能功能障碍。
Sci Rep. 2021 Sep 30;11(1):19412. doi: 10.1038/s41598-021-99025-1.
5
Ventral Tegmental Area Disconnection Contributes Two Years Early to Correctly Classify Patients Converted to Alzheimer's Disease: Implications for Treatment.腹侧被盖区断开有助于提前两年正确分类转化为阿尔茨海默病的患者：对治疗的影响。
J Alzheimers Dis. 2021;82(3):985-1000. doi: 10.3233/JAD-210171.
6
Nilotinib restores memory function by preventing dopaminergic neuron degeneration in a mouse model of Alzheimer's Disease.尼洛替尼通过防止阿尔茨海默病小鼠模型中多巴胺能神经元退化来恢复记忆功能。
Prog Neurobiol. 2021 Jul;202:102031. doi: 10.1016/j.pneurobio.2021.102031. Epub 2021 Mar 5.
7
Loss of Midbrain Dopamine Neurons and Altered Apomorphine EEG Effects in the 5xFAD Mouse Model of Alzheimer's Disease.阿尔茨海默病 5xFAD 小鼠模型中中脑多巴胺神经元的丢失和阿扑吗啡 EEG 效应的改变。
J Alzheimers Dis. 2019;70(1):241-256. doi: 10.3233/JAD-181246.
8
Volume and Connectivity of the Ventral Tegmental Area are Linked to Neurocognitive Signatures of Alzheimer's Disease in Humans.腹侧被盖区的体积和连通性与人类阿尔茨海默病的神经认知特征有关。
J Alzheimers Dis. 2018;63(1):167-180. doi: 10.3233/JAD-171018.
9
Memantine for the Treatment of Dementia: A Review on its Current and Future Applications.盐酸美金刚治疗痴呆：对其现有和未来应用的综述。
J Alzheimers Dis. 2018;62(3):1223-1240. doi: 10.3233/JAD-170672.
10
Calcium signaling and molecular mechanisms underlying neurodegenerative diseases.钙信号与神经退行性疾病的分子机制。
Cell Calcium. 2018 Mar;70:87-94. doi: 10.1016/j.ceca.2017.06.008. Epub 2017 Jun 30.