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慢性静脉疾病及其与糖尿病的交集。

Chronic Venous Disease and Its Intersections With Diabetes Mellitus.

机构信息

Diabetes Centre, Institute for Clinical and Experimental Medicine, Praha 4, Czech Republic.

出版信息

Physiol Res. 2023 Jul 14;72(3):280-286. doi: 10.33549/physiolres.935033.

Abstract

Chronic venous disease (CVD) is a vascular disorder in which blood return is severely compromised and CVD is usually characterized by venous hypertension. Along with obesity and diabetes mellitus, CVD is one of the most common civilization diseases. In general, the estimated prevalence of CVD ranges from 60-80 %. Early diagnosis and adequate treatment are important for preventing progression to more severe stages of the disease like venous leg ulcers. Clinical manifestations of CVD in initial stages of the disease are often asymptomatic. However, as CVD progresses, symptoms begin to develop. Treatment of CVD could be divided into conservative and surgical. Conservative therapy consists of compression, pharmacological treatment and lifestyle change. In cases where conservative therapy is ineffective, surgical or endovascular treatment may be required. The intersections between diabetes mellitus (DM) and CVD are not to be underestimated. CVD and DM have often the same risk factors. Symptoms of CVD can be modified by late complications of DM, but the incidence of different CVD degrees seems to be the same as in diabetics as in non-diabetics population. We are particularly concerned in diabetics about worse compliance with treatment due to their often-poorer adherence to treatment of DM and lifestyle changes. Moreover, there exist a higher risk of CVD and peripheral arterial disease in diabetics patients. Patients with CVD should always be inspected for the presence of DM, considering its presence can have a bearing on CVD symptoms, diagnostic procedures, and therapeutic strategies.

摘要

慢性静脉疾病(CVD)是一种血管疾病,血液回流严重受损,CVD 通常以静脉高压为特征。与肥胖和糖尿病一样,CVD 是最常见的文明病之一。一般来说,CVD 的估计患病率在 60-80%之间。早期诊断和充分治疗对于预防疾病进展到更严重的阶段,如静脉腿部溃疡,非常重要。CVD 在疾病早期的临床表现通常是无症状的。然而,随着疾病的进展,症状开始出现。CVD 的治疗可以分为保守治疗和手术治疗。保守治疗包括压迫、药物治疗和生活方式改变。在保守治疗无效的情况下,可能需要手术或血管内治疗。糖尿病(DM)和 CVD 之间的交集不容忽视。CVD 和 DM 通常有相同的危险因素。DM 的晚期并发症可以改变 CVD 的症状,但不同 CVD 程度的发病率似乎与非糖尿病患者和糖尿病患者相同。我们特别关注糖尿病患者,因为他们通常对 DM 的治疗和生活方式改变的依从性较差,导致治疗的依从性更差。此外,糖尿病患者患 CVD 和外周动脉疾病的风险更高。患有 CVD 的患者应始终检查是否存在 DM,因为 DM 的存在可能会影响 CVD 的症状、诊断程序和治疗策略。

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