Sharma S K, Pande J N, Guleria J S
J Asthma. 1986;23(1):15-7. doi: 10.3109/02770908609077465.
This article describes the effect of nifedipine, a calcium antagonist, on exercise-induced asthma (EIA). Effect of sublingual administration of 20 mg of nifedipine or placebo was studied in randomized double-blind manner on separate days in 19 extrinsic asthmatic subjects. Nifedipine was found to be significantly effective in abolishing the exercise-induced decrease in forced vital capacity (FVC) and maximal expiratory flows (p less than 0.001). There were no significant changes in heart rate and blood pressure after nifedipine.
本文描述了钙拮抗剂硝苯地平对运动诱发性哮喘（EIA）的影响。以随机双盲方式，在不同日期对19名外源性哮喘患者分别给予20毫克硝苯地平或安慰剂舌下含服，并研究其效果。结果发现，硝苯地平能显著有效消除运动诱发的用力肺活量（FVC）和最大呼气流量下降（p<0.001）。服用硝苯地平后，心率和血压无显著变化。
