Zheng Gangfu, Yu Nengfeng, Du Jiaqi, Zheng Yichun
Department of Urology, The Fourth Affiliated Hospital, International Institutes of Medicine, Zhejiang University School of Medicine, Yiwu, CHN.
Cureus. 2023 Jun 14;15(6):e40433. doi: 10.7759/cureus.40433. eCollection 2023 Jun.
Lymphoepithelioma-like carcinoma (LELC) was characterized by epithelial neoplastic cells developing in solid or incohesive sheets mixed with a noticeable lymphoid infiltration. Lymphoepithelioma-like carcinoma of the bladder (LELCB), which was first described by Zukerberg, is a rare variant of LELC. Here we reported a new case of LELCB occurring in a 70-year-old woman presenting with hematuria. Computed tomography (CT) and cystoscopy revealed a tumor on the left upper wall of the bladder. A partial cystectomy was finally performed. Pathological and immunohistochemical analysis revealed LELCB. After receiving systemic adjuvant chemotherapy, the patient conducted a 25-month follow-up without experiencing a recurrence.
淋巴上皮瘤样癌(LELC)的特征是上皮性肿瘤细胞呈实性或松散片状生长,并伴有明显的淋巴细胞浸润。膀胱淋巴上皮瘤样癌(LELCB)由祖克伯格首次描述,是LELC的一种罕见变体。我们在此报告一例发生于一名70岁血尿女性的LELCB新病例。计算机断层扫描(CT)和膀胱镜检查显示膀胱左上壁有一个肿瘤。最终实施了部分膀胱切除术。病理和免疫组化分析显示为LELCB。接受全身辅助化疗后,患者进行了25个月的随访,未出现复发。