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病毒引发的乳糜泻:一例报告

Viral Triggered Celiac Disease: A Case Report.

作者信息

Welch Nicole L, Welch Tyler, Songtanin Busara

机构信息

Internal Medicine, Texas Tech University Health Sciences Center Lubbock Campus, Lubbock, USA.

Family Medicine, Baptist Health-UAMS (University of Arkansas for Medical Sciences), North Little Rock, USA.

出版信息

Cureus. 2023 Jun 14;15(6):e40429. doi: 10.7759/cureus.40429. eCollection 2023 Jun.

Abstract

Celiac disease (CD) is an autoimmune condition presenting with a wide variety of nonspecific gastrointestinal symptoms. It can be difficult to diagnose due to the vagueness of complaints such as diarrhea, anemia due to malabsorption, vitamin or electrolyte deficiencies, and/or failure to thrive. This condition is characterized by a sensitivity to ingested gluten-containing compounds. Blood tests can be used for screening, though confirmatory testing by a small intestine biopsy is needed for diagnosis. Viral infections can trigger autoimmune conditions in individuals. It is possible that viral infections, such as Ebsetein-Barr virus(EBV) or Cytomegalovirus (CMV), can trigger the clinical presentation of celiac disease in certain individuals with genetic predispositions. Early recognition of celiac disease is important to prevent both short and long-term complications and improve the quality of life for the individual. Here, we discuss a case where the patient developed celiac disease only months after a diagnosis of mononucleosis.

摘要

乳糜泻(CD)是一种自身免疫性疾病,表现为各种各样的非特异性胃肠道症状。由于腹泻、吸收不良引起的贫血、维生素或电解质缺乏和/或发育不良等症状的模糊性,其诊断可能会很困难。这种疾病的特点是对摄入的含麸质化合物敏感。血液检查可用于筛查,但诊断需要通过小肠活检进行确诊。病毒感染可引发个体的自身免疫性疾病。诸如爱泼斯坦-巴尔病毒(EBV)或巨细胞病毒(CMV)等病毒感染有可能在某些具有遗传易感性的个体中引发乳糜泻的临床表现。早期识别乳糜泻对于预防短期和长期并发症以及提高个体生活质量很重要。在此,我们讨论一例患者在诊断单核细胞增多症仅数月后就患上乳糜泻的病例。

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本文引用的文献

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