Academy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin, China.
Division of Academic & Cultural Activities, Academic Divisions of the Chinese Academy of Sciences, Beijing, China.
Adv Exp Med Biol. 2023;1199:87-106. doi: 10.1007/978-981-32-9902-3_5.
It is vitally important to guide or navigate therapeutic proceedings with a direct and visual approach in order to carefully undertake precision medical manipulations and efficiently evaluate the treatments. Imaging-navigated surgery is one of the common and prevailing technologies to realize this target, and more importantly it merges visualized medicine into next-generation theranostic paradigms in modern medicine. Endoscopes, surgical robots, and nanorobots are three major domains in terms of imaging-navigated surgery. The history of endoscopy has seen upgraded developments since the early 1800s. In contrast, surgical robots have been widely used and investigated in recent years, and they came into clinical uses only in the past decades. Nanorobots which closely depend on innovated and multifunctional biomaterials are still in their infancy. All these imaging-navigated technologies show similar and apparent advantages such as minimal invasiveness, minimized pain, positive prognosis, and relatively expected recovery, which have greatly improved surgery efficiency and patients' life quality. Therefore, the imaging-navigated surgery will be discussed in this chapter, and advanced clinical and preclinical medical applications will also be demonstrated for a diverse readers and comprehensive understanding.
为了能够仔细进行精准的医学操作并有效地评估治疗效果,用直接且可视化的方法来指导或导航治疗过程至关重要。影像导航手术是实现这一目标的常见且流行的技术之一,更重要的是,它将可视化医学融入了现代医学的下一代治疗诊断模式中。内窥镜、手术机器人和纳米机器人是影像导航手术的三个主要领域。自 19 世纪初以来,内窥镜的历史已经看到了升级发展。相比之下,手术机器人近年来得到了广泛的应用和研究,并且仅在过去几十年才开始在临床应用。纳米机器人严重依赖于创新和多功能生物材料,目前仍处于起步阶段。所有这些影像导航技术都显示出类似的明显优势,如微创性、最小化疼痛、积极的预后和相对可预期的恢复,这大大提高了手术效率和患者的生活质量。因此,本章将讨论影像导航手术,并为不同的读者展示先进的临床和临床前医学应用,以实现全面的理解。