Cartes Cristian, Segovia Christian, Calonge Margarita, Figueiredo Francisco C
Unidad Oftalmología, Departamento de Especialidades, Facultad de Medicina, Universidad de la Frontera, Temuco, Chile.
Centro de la Visión, Red Centro Oftalmológico Laser, Santiago, Chile.
Heliyon. 2023 Jun 7;9(6):e16995. doi: 10.1016/j.heliyon.2023.e16995. eCollection 2023 Jun.
To evaluate patterns and opinion from international experts with respect to dry eye disease (DED) diagnosis in clinical practice.
An online survey was distributed to worldwide DED experts. The use of diagnosis tests was evaluated including: symptoms questionnaires, functional tests, tear stability, tear volume, tear composition, surface damage and inflammation, and eyelid assessment. After the subjective importance of symptoms, tear break up time (TBUT), non-invasive TBUT, Schirmer's test, tear meniscus height, tear osmolarity, tear metalloproteinase 9, blepharitis assessment and non-contact meibography was evaluated according to likert scale.
The survey was sent to 109 experts, and 77 completed the questionnaire (rate of response = 70.6%). Most of the participants were from North America (27%) and Europe (40%). A majority of respondents (73%) diagnose DED using clinical signs and symptoms, but not fulfilling a specific criteria. Seventy-six participants (98.7%) use symptoms questionnaires. All participants evaluate damage to ocular surface, and fluorescein staining is the most frequent method used (92%). Also, all the respondents perform meibomian gland and blepharitis assessment. On the other hand, only 69.8% evaluate tear composition, being osmolarity the most common test used (66.2%). Regarding to the importance of tests, TBUT (p = 0.002) and Schirmer's (p = 0.021) were found to be more important to experts from Europe than North America. No differences were found in any other test (p > 0.05).
This survey offers updated and day-to-day diagnostic clinical practice by DED worldwide experts. The results highlight the importance of symptoms and clinical signs, but not necessarily following a strict criteria.
评估国际专家在临床实践中对干眼疾病(DED)诊断的模式和观点。
向全球干眼疾病专家开展在线调查。评估了诊断测试的使用情况,包括:症状问卷、功能测试、泪液稳定性、泪液量、泪液成分、眼表损伤与炎症以及眼睑评估。根据李克特量表评估了症状、泪膜破裂时间(TBUT)、非侵入性TBUT、施密特试验、泪河高度、泪液渗透压、泪液金属蛋白酶9、睑缘炎评估和非接触式睑板腺成像的主观重要性。
该调查发送给了109位专家,77位完成了问卷(回复率 = 70.6%)。大多数参与者来自北美(27%)和欧洲(40%)。大多数受访者(73%)使用临床体征和症状诊断干眼疾病,但未满足特定标准。76名参与者(98.7%)使用症状问卷。所有参与者都评估眼表损伤,荧光素染色是最常用的方法(92%)。此外,所有受访者都进行睑板腺和睑缘炎评估。另一方面,只有69.8%的人评估泪液成分,渗透压是最常用的测试(66.2%)。关于测试的重要性,发现TBUT(p = 0.002)和施密特试验(p = 0.021)对欧洲专家比北美专家更重要。在任何其他测试中均未发现差异(p > 0.05)。
本次调查提供了全球干眼疾病专家最新的日常诊断临床实践情况。结果强调了症状和临床体征的重要性,但不一定遵循严格标准。