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由西氏曲霉引起的肺曲霉病罕见病例:一例报告

Uncommon Occurrence of Pulmonary Aspergillosis Caused by Aspergillus sydowii: A Case Report.

作者信息

Nagashima Akimichi, Nagato Tadashi, Kobori Tomoko, Nagi Minoru, Okochi Yasumi

机构信息

Department of Respiratory Medicine, Japan Community Health Care Organization Tokyo Yamate Medical Center, Tokyo, JPN.

Department of Fungal Infection/Antimicrobial Resistance Research Center, National Institute of Infectious Diseases, Tokyo, JPN.

出版信息

Cureus. 2023 Dec 30;15(12):e51353. doi: 10.7759/cureus.51353. eCollection 2023 Dec.

Abstract

This case report presents an unusual occurrence of pulmonary aspergillosis caused by in a 26-year-old male patient. The patient is from Nepal and had no significant medical history and was previously in good health. Chest computed tomography (CT) scans revealed localized bronchiectasis primarily in the left inferior lingular segment and the left lower lobe. Subsequently, bronchial lavage fluid was collected, and a comprehensive culture examination was conducted to confirm the cause of the infection. While typically predominates as the cause of pulmonary aspergillosis, our bronchial lavage fluid culture revealed the presence of a filamentous fungus, identified as through molecular analysis. Thus, we conclusively identified this particular strain of fungus as the etiological factor behind the patient's condition. Notably, pulmonary aspergillosis due to is exceedingly rare, and we present this case alongside relevant prior data for comprehensive clinical insight. This case underscores the clinical significance of as a fungal pathogen, emphasizing the importance of early recognition and managing fungal infections.

摘要

本病例报告介绍了一名26岁男性患者发生的由[具体真菌名称未给出]引起的罕见肺曲霉病。该患者来自尼泊尔,无重大病史,此前身体健康。胸部计算机断层扫描(CT)显示主要在左下舌段和左肺下叶出现局限性支气管扩张。随后,收集了支气管灌洗液,并进行了全面的培养检查以确定感染原因。虽然[常见真菌名称未给出]通常是肺曲霉病的主要病因,但我们的支气管灌洗液培养显示存在一种丝状真菌,通过分子分析鉴定为[具体真菌名称未给出]。因此,我们最终确定这种特定的真菌菌株是患者病情的病因。值得注意的是,由[具体真菌名称未给出]引起的肺曲霉病极为罕见,我们展示此病例并附上相关既往数据以供全面的临床参考。 本病例强调了[具体真菌名称未给出]作为真菌病原体的临床意义,强调了早期识别和管理真菌感染的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a07/10827003/1dc19f644869/cureus-0015-00000051353-i01.jpg

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