College of Biological Sciences, China Agricultural University, Beijing 100193, China; College of Life Sciences, Henan Agricultural University, Zhengzhou 450002, China.
College of Life Sciences, Henan Agricultural University, Zhengzhou 450002, China.
Plant Commun. 2024 Jan 8;5(1):100663. doi: 10.1016/j.xplc.2023.100663. Epub 2023 Jul 26.
Membraneless biomolecular condensates play important roles in both normal biological activities and responses to environmental stimuli in living organisms. Liquid‒liquid phase separation (LLPS) is an organizational mechanism that has emerged in recent years to explain the formation of biomolecular condensates. In the past decade, advances in LLPS research have contributed to breakthroughs in disease fields. By contrast, although LLPS research in plants has progressed over the past 5 years, it has been concentrated on the model plant Arabidopsis, which has limited relevance to agricultural production. In this review, we provide an overview of recently reported advances in LLPS in plants, with a particular focus on photomorphogenesis, flowering, and abiotic and biotic stress responses. We propose that many potential LLPS proteins also exist in crops and may affect crop growth, development, and stress resistance. This possibility presents a great challenge as well as an opportunity for rigorous scientific research on the biological functions and applications of LLPS in crops.
无膜生物分子凝聚物在生物的正常生理活动和对环境刺激的反应中都起着重要作用。液-液相分离（LLPS）是近年来出现的一种组织机制，用于解释生物分子凝聚物的形成。在过去的十年中，LLPS 研究的进展为疾病领域的突破做出了贡献。相比之下，尽管过去 5 年来植物中的 LLPS 研究取得了进展，但主要集中在模式植物拟南芥上，这与农业生产的相关性有限。在这篇综述中，我们概述了最近报道的植物中 LLPS 的进展，特别关注光形态建成、开花以及非生物和生物胁迫反应。我们提出，许多潜在的 LLPS 蛋白也存在于作物中，可能会影响作物的生长、发育和抗胁迫能力。这一可能性为在作物中对 LLPS 的生物学功能和应用进行严格的科学研究既带来了挑战，也带来了机遇。
