Zhu Yan, Wu Di, Sun Kewei, Chen Xianglong, Wang Yifan, He Yang, Xiao Wei
Department of Military Medical Psychology, Air Force Medical University, Xi'an 710032, China.
Brain Sci. 2023 Jul 4;13(7):1026. doi: 10.3390/brainsci13071026.
(1) Background: The Go/NoGo task and color-word Stroop task were used to investigate the effect of applying different frequency bands of neural oscillations to the lDLPFC on inhibitory control modulation. (2) Methods: Participants were randomly categorized into four groups and received HD-tACS at 6, 10, and 20 Hz or sham stimulation at 1.5 mA for 20 min. All participants performed a color-word Stroop task and Go/NoGo task before and immediately after the stimulation; closed-eye resting-state EEG signals were acquired for 3 min before and after the tasks. (3) Results: There were no significant differences in the Go/NoGo behavioral indices task across the four groups. In the color-word Stroop task, the Stroop effect of response time was significantly reduced by 6 and 10 Hz stimulations compared to sham stimulation, and the Stroop effect of accuracy was significantly reduced by 10 Hz stimulation. There were no significant differences in the frequency range-specific (delta, theta, alpha, beta, or gamma) resting EEG power before and after stimulation. (4) Conclusions: HD-tACS at 6 and 10 Hz effectively improved participants' performance on the color-word Stroop task, demonstrating the importance of the lDLPFC in interference inhibition and supporting a causal relationship between theta and alpha oscillations in interference inhibition.
(1) 背景：采用Go/NoGo任务和色词Stroop任务来研究将不同频段的神经振荡应用于左背外侧前额叶皮质（lDLPFC）对抑制控制调节的影响。(2) 方法：参与者被随机分为四组，分别接受6赫兹、10赫兹和20赫兹的高分辨率经颅交流电刺激（HD-tACS）或1.5毫安的伪刺激，持续20分钟。所有参与者在刺激前和刺激后立即进行色词Stroop任务和Go/NoGo任务；在任务前后采集3分钟的闭眼静息态脑电图信号。(3) 结果：四组在Go/NoGo行为指标任务上没有显著差异。在色词Stroop任务中，与伪刺激相比，6赫兹和10赫兹的刺激显著降低了反应时间的Stroop效应，10赫兹的刺激显著降低了准确率的Stroop效应。刺激前后在特定频率范围（δ、θ、α、β或γ）的静息脑电图功率没有显著差异。(4) 结论：6赫兹和10赫兹的HD-tACS有效改善了参与者在色词Stroop任务中的表现，证明了lDLPFC在干扰抑制中的重要性，并支持了θ和α振荡在干扰抑制中的因果关系。
