Vinolo-Gil Maria Jesus, García-Campanario Ismael, Estebanez-Pérez María-José, Pastora-Bernal José-Manuel, Rodríguez-Huguet Manuel, Martín-Vega Francisco Javier
Department of Nursing and Physiotherapy, University of Cadiz, 11003 Cadiz, Spain.
Institute for Biomedical Research and Innovation of Cádiz, 11009 Cadiz, Spain.
Healthcare (Basel). 2023 Jul 19;11(14):2062. doi: 10.3390/healthcare11142062.
Cancer, being a highly widespread disease on a global scale, has prompted researchers to explore innovative treatment approaches. In this regard, blood flow restriction has emerged as a promising procedure utilized in diverse clinical populations with favorable results including improvements in muscle strength, cardiovascular function, and postoperative recovery. The aim of this systematic review was to assess the efficacy of blood flow restriction in cancer survivors.
An investigation was carried out using various databases until February 2023: PubMed, Scientific Electronic Library Online, Physiotherapy Evidence Database, Scopus, Web of Science, Cochrane Plus, SPORTDiscus, Physiotherapy and Podiatry of the Complutense University of Madrid, ScienceDirect, ProQuest, Research Library, Cumulative Index of Nursing and Allied Literature Complete Journal Storage, and the gray literature. To assess the methodological quality of the studies, the PEDro scale was utilized, and the Cochrane Collaboration tool was employed to evaluate the risk of bias.
Five articles found that blood flow restriction was beneficial in improving several factors, including quality of life, physical function, strength, and lean mass, and in reducing postoperative complications and the length of hospital stay.
Blood flow restriction can be a viable and effective treatment option. It is important to note that the caution with which one should interpret these results is due to the restricted quantity of articles and significant variation, and future research should concentrate on tailoring the application to individual patients, optimizing load progression, ensuring long-term follow-up, and enhancing the methodological rigor of studies, such as implementing sample blinding.
癌症作为一种在全球范围内广泛传播的疾病，促使研究人员探索创新的治疗方法。在这方面，血流限制已成为一种有前景的治疗手段，应用于不同临床人群，取得了良好效果，包括肌肉力量、心血管功能和术后恢复的改善。本系统评价的目的是评估血流限制对癌症幸存者的疗效。
截至2023年2月，使用多个数据库进行了一项调查：PubMed、科学电子图书馆在线、物理治疗证据数据库、Scopus、科学网、Cochrane Plus、SPORTDiscus、马德里康普顿斯大学物理治疗与足病学、ScienceDirect、ProQuest、研究图书馆、护理及相关文献累积索引完整期刊库以及灰色文献。为评估研究的方法学质量，使用了PEDro量表，并采用Cochrane协作工具评估偏倚风险。
五篇文章发现，血流限制有助于改善包括生活质量、身体功能、力量和瘦体重在内的多个因素，并减少术后并发症和住院时间。
血流限制可能是一种可行且有效的治疗选择。需要注意的是，由于文章数量有限且存在显著差异，对这些结果的解读应谨慎，未来的研究应集中于针对个体患者调整应用方法、优化负荷进展、确保长期随访以及提高研究的方法学严谨性，如实施样本盲法。
