Latalska Małgorzata, Bartosińska Joanna, Dresler Sławomir, Toro Mario Damiano, Krasowska Dorota, Rejdak Robert
Department of General and Pediatric Ophthalmology, Medical University of Lublin, 20-079 Lublin, Poland.
Department of Cosmetology and Aesthetic Medicine, Medical University of Lublin, 20-093 Lublin, Poland.
J Clin Med. 2023 Jul 21;12(14):4817. doi: 10.3390/jcm12144817.
This study seeks to evaluate the results of nailfold videocapillaroscopies (NVCs) among patients with central serous chorioretinopathy (CSC) and their correlation with the choroid and retinal parameters.
The examined group included 152 patients with acute, recurrent, chronic and neovascular CSC (34 F, 118 M, mean age 45.9 ± 8.9) and 41 healthy controls (12 F, 29 M, mean age 47 ± 11.5). The NVC examination, ophthalmoscopy, angio-OCT and OCT were performed. In addition, the medical history regarding chronic general disorders and known risk factors were recorded.
Abnormal NVC patterns and the dilated apical part of capillaries were found only in CSC patients ( = 0.000). Neoangiogenesis was observed in 25 acute (58.14%), 22 recurrent (42.31%), 16 chronic (36.36%) and 5 neovascular patients (45.45%) and 2 control subjects (4.88%) ( = 0.000). Glomerular capillaries were found in 8 acute (18.6%), 17 recurrent (31.48%), 25 chronic (56.82%) and 8 neovascular patients (72.73%) ( = 0.000). Meandering capillaries were more common in acute and recurrent CSC and glomerular capillaries were more common in chronic and aneurysmal dilations in neovascular CSC.
The observed digital microcirculation abnormalities in patients with CSC, such as dilation, meandering, tortuosity and glomerular, may confirm systemic micro-vasculopathy. The potential role of the NVC examination in assessing the CSC prognosis requires further evaluation.
本研究旨在评估中心性浆液性脉络膜视网膜病变（CSC）患者的甲襞视频毛细血管镜检查（NVC）结果及其与脉络膜和视网膜参数的相关性。
受检组包括152例急性、复发性、慢性和新生血管性CSC患者（女性34例，男性118例，平均年龄45.9±8.9岁）和41例健康对照者（女性12例，男性29例，平均年龄47±11.5岁）。进行了NVC检查、检眼镜检查、血管光学相干断层扫描（angio - OCT）和光学相干断层扫描（OCT）。此外，记录了有关慢性全身性疾病和已知危险因素的病史。
仅在CSC患者中发现异常NVC模式和毛细血管顶端扩张（P = 0.000）。在25例急性患者（58.14%）、22例复发性患者（42.31%）、16例慢性患者（36.36%）和5例新生血管性患者（45.45%）以及2例对照者（4.88%）中观察到新生血管形成（P = 0.000）。在8例急性患者（18.6%）、17例复发性患者（31.48%）、25例慢性患者（56.82%）和8例新生血管性患者（72.73%）中发现肾小球样毛细血管（P = 0.000）。迂曲毛细血管在急性和复发性CSC中更常见，而肾小球样毛细血管在慢性和新生血管性CSC的动脉瘤样扩张中更常见。
在CSC患者中观察到的数字微循环异常，如扩张、迂曲、扭曲和肾小球样改变，可能证实存在全身性微血管病变。NVC检查在评估CSC预后中的潜在作用需要进一步评估。
