Latalska Małgorzata, Bartosińska Joanna, Kosior-Jarecka Ewa, Krasowska Dorota, Mackiewicz Jerzy
Department of Vitreoretinal Surgery, Medical University of Lublin, 20-079 Lublin, Poland.
Department of Cosmetology and Aesthetic Medicine, Medical University of Lublin, 20-093 Lublin, Poland.
J Clin Med. 2020 Nov 30;9(12):3891. doi: 10.3390/jcm9123891.
The aim of the study was to evaluate the results of nailfold videocapillaroscopy (NVC) in patients with central serous chorioretinopathy (CSC) and their correlation with different functional, morphological features and general risk factors.
The examined group included 59 CSC patients (14 F, 45 M, mean age 47.2 ± 9.4) and 53 healthy controls (13 F, 40 M, mean age 46 ± 11.5). The NVC was qualified as a normal or abnormal pattern. In the CSC group, the ophthalmoscopy, angio-Optical Coherence Tomography (OCT-A), OCT and microperimetry were performed. The medical history regarding CSC, chronic general disorders and known risk factors was recorded.
In the CSC group an abnormal NVC pattern was more common (33.88% CSC vs. 7.54%, < 0.001). Dilated apical part of capillaries, microaneurysmal dilatation, megacapillaries, fresh microhaemorrhages, bizarre and broken capillaries were observed only in CSC patients. Dilation of capillaries (47.56% vs. 13.21%, = 0.004), ramified capillaries and neoangiogenesis (38.98% vs. 5.66%, < 0.001), glomerular loops (32.20% vs. 1.88% < 0.001) were more frequent in the CSC group.
The presence of various NVC abnormalities confirms microvascular involvement in CSC pathogenesis. The results correlate with visual acuity, microperimetry, OCT data and stress. The NVC technique may play a useful diagnostic and prognostic role in CSC.
本研究旨在评估中心性浆液性脉络膜视网膜病变（CSC）患者的甲襞视频毛细血管镜检查（NVC）结果，以及这些结果与不同功能、形态学特征和一般危险因素之间的相关性。
受检组包括59例CSC患者（14例女性，45例男性，平均年龄47.2±9.4岁）和53名健康对照者（13例女性，40例男性，平均年龄46±11.5岁）。NVC结果被判定为正常或异常模式。在CSC组中，进行了眼底镜检查、血管光学相干断层扫描（OCT - A）、OCT和微视野检查。记录了有关CSC、慢性全身性疾病和已知危险因素的病史。
在CSC组中，异常NVC模式更为常见（CSC组为33.88%，对照组为7.54%，<0.001）。仅在CSC患者中观察到毛细血管顶端扩张、微动脉瘤样扩张、大毛细血管、新鲜微出血、奇异和断裂的毛细血管。CSC组中毛细血管扩张（47.56%对13.21%，=0.004）、分支状毛细血管和新生血管形成（38.
