Vasluianu Roxana-Ionela, Dima Ana Maria, Bobu Livia, Murariu Alice, Stamatin Ovidiu, Baciu Elena-Raluca, Luca Elena-Odette
Department of Prosthodontics, Faculty of Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.
Independent Researcher, 700506 Iasi, Romania.
J Funct Biomater. 2025 Mar 20;16(3):110. doi: 10.3390/jfb16030110.
We are committed to writing this narrative review given that carbon-based nanomaterials are revolutionizing dental medicine. Since the groundbreaking discovery of carbon nanotubes in 1991, their dental applications have skyrocketed. The numbers speak for themselves: in 2024, the global carbon nanotubes market hit USD 1.3 billion and is set to double to USD 2.6 billion by 2029. Over the past few decades, various forms of carbon nanomaterials have been integrated into dental practices, elevating the quality and effectiveness of dental treatments. They represent a transformative advancement in dentistry, offering numerous benefits such as augmented mechanical properties, antimicrobial activity, and potential for regenerative applications. Both carbon nanotubes (CNTs) and carbon dots (CDs) are derived from carbon and integral to nanotechnology, showcasing the versatility of carbon nanostructures and delivering cutting-edge solutions across diverse domains, such as electronics, materials science, and biomedicine. CNTs are ambitiously examined for their capability to reinforce dental materials, develop biosensors for detecting oral diseases, and even deliver therapeutic agents directly to affected tissues. This review synthesizes their current applications, underscores their interdisciplinary value in bridging nanotechnology and dentistry, identifies key barriers to clinical adoption, and discusses hybrid strategies warranting further research to advance implementation.
鉴于碳基纳米材料正在彻底改变牙科医学，我们致力于撰写这篇叙述性综述。自1991年碳纳米管被开创性发现以来，它们在牙科领域的应用呈火箭式增长。数据说明了一切：2024年，全球碳纳米管市场达到13亿美元，到2029年预计将翻一番，达到26亿美元。在过去几十年里，各种形式的碳纳米材料已被整合到牙科实践中，提高了牙科治疗的质量和效果。它们代表了牙科领域的一项变革性进展，具有诸多益处，如增强机械性能、抗菌活性以及再生应用潜力。碳纳米管（CNTs）和碳点（CDs）都源自碳，是纳米技术的重要组成部分，展示了碳纳米结构的多功能性，并在电子、材料科学和生物医学等不同领域提供前沿解决方案。人们对碳纳米管增强牙科材料的能力、开发用于检测口腔疾病的生物传感器以及甚至将治疗剂直接递送至受影响组织的能力进行了深入研究。本综述综合了它们目前的应用，强调了它们在纳米技术与牙科之间的跨学科价值，确定了临床应用的关键障碍，并讨论了需要进一步研究以推进实施的混合策略。
