Laboratório das Interações Vírus Hospedeiros, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro 210400-900, RJ, Brazil.
Núcleo Operacional Sentinela de Mosquitos Vetores-Nosmove, Fundação Oswaldo Cruz, Rio de Janeiro 21400-900, RJ, Brazil.
Viruses. 2023 Jul 1;15(7):1496. doi: 10.3390/v15071496.
Dengue (DENV), chikungunya (CHIKV), and Zika (ZIKV) virus infections are widespread throughout the Rio de Janeiro state. The co-circulation of these emergent arboviruses constitutes a serious public health problem, resulting in outbreaks that can spatially and temporally overlap. Environmental conditions favor the presence, maintenance, and expansion of , the primary vector of these urban arboviruses. This study assessed the detection of clusters of urban arboviruses in the Rio de Janeiro state from 2010 to 2019. Notified cases of dengue, chikungunya, and Zika were grouped by year according to the onset of symptoms and their municipality of residence. The study period recorded the highest number of dengue epidemics in the state along with the simultaneous circulation of chikungunya and Zika viruses. The analyzes showed that the central municipalities of the metropolitan regions were associated with higher risk areas. Central municipalities in metropolitan regions were the first most likely clusters for dengue and Zika, and the second most likely cluster for chikungunya. Furthermore, the northwest and north regions were comprised clusters with the highest relative risk for the three arboviruses, underscoring the impact of these arboviruses in less densely populated regions of Brazil. The identification of high-risk areas over time highlights the need for effective control measures, targeted prevention and control interventions for these urban arboviral diseases.
登革热（DENV）、基孔肯雅热（CHIKV）和寨卡热（ZIKV）病毒感染在里约热内卢州广泛传播。这些新兴虫媒病毒的共同传播构成了严重的公共卫生问题，导致疫情在空间和时间上重叠。环境条件有利于这些城市虫媒病毒的存在、维持和扩散。本研究评估了 2010 年至 2019 年里约热内卢州城市虫媒病毒群集的检测情况。根据症状发作和居住地的不同，将登革热、基孔肯雅热和寨卡热的已报告病例按年份分组。研究期间，该州记录了登革热疫情数量最多，同时还存在基孔肯雅热和寨卡病毒的循环。分析表明，大都市地区的中心城市与高风险地区有关。大都市地区的中心城市是登革热和寨卡热的第一个最有可能的集群，也是基孔肯雅热的第二个最有可能的集群。此外，西北部和北部地区是三种虫媒病毒的相对风险最高的集群，突显了这些虫媒病毒对巴西人口密度较低地区的影响。随着时间的推移，高风险地区的确定凸显了需要采取有效的控制措施，针对这些城市虫媒病毒病进行有针对性的预防和控制干预。
