Li Min, Tao Meng, Zhang Yue, Pan Ruoxin, Gu Duoduo, Xu Yang
Department of Dermatology, the First Affiliated Hospital of Nanjing Medical University (Jiangsu Province Hospital), Nanjing, 210029, People's Republic of China.
Clin Cosmet Investig Dermatol. 2023 Jul 25;16:1949-1954. doi: 10.2147/CCID.S417070. eCollection 2023.
Morbihan disease is a rare entity involving the upper two-thirds of the face and characterized by chronic erythematous edema, which is recalcitrant to the traditional therapy of rosacea. We report a case of Morbihan disease effectively treated with macro-focused high-intensity focus ultrasound (MF-HIFU). After MF-HIFU treatment, an obvious reduction in swelling was observed with decreased erythema and hyperalgesia. In addition, in-vitro experiments were conducted to measure the actual temperature of the skin tissue under the epidermis. The results of the in-vitro experiments showed that the temperature plateau in the skin sample was reached at approximately 42°C after 5-min treatment or longer. MF-HIFU might be a promising energy-based therapy for Morbihan disease.
莫尔比昂病是一种罕见病症，累及面部上三分之二，其特征为慢性红斑性水肿，对酒渣鼻的传统治疗方法无效。我们报告一例用宏观聚焦高强度聚焦超声（MF-HIFU）有效治疗的莫尔比昂病病例。MF-HIFU治疗后，观察到肿胀明显减轻，红斑和痛觉过敏也有所减轻。此外，还进行了体外实验以测量表皮下皮肤组织的实际温度。体外实验结果表明，处理5分钟或更长时间后，皮肤样本中的温度在约42°C时达到稳定状态。MF-HIFU可能是一种有前景的基于能量的莫尔比昂病治疗方法。
