检测或排除连锁异质性所需的家系数量。
The number of families required to detect or exclude linkage heterogeneity.
作者信息
Ott J
出版信息
Am J Hum Genet. 1986 Aug;39(2):159-65.
Abstract
Under the assumption of two family types, one with linkage and one without linkage, the number of phase-known double-backcross families required to detect heterogeneity is investigated. The case of testing for heterogeneity with two offspring per family is shown to be formally equivalent to testing for inbreeding effects in a sample of unrelated individuals.
摘要
在假设有两种家系类型（一种存在连锁，一种不存在连锁）的情况下，研究了检测异质性所需的已知相双回交家系的数量。结果表明，每个家系有两个后代时检测异质性的情况在形式上等同于在无关个体样本中检测近亲繁殖效应。
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本文引用的文献
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