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Multi-ancestry study of the genetics of problematic alcohol use in over 1 million individuals.多血统个体超过 100 万人的问题性饮酒使用的遗传学研究。
Nat Med. 2023 Dec;29(12):3184-3192. doi: 10.1038/s41591-023-02653-5. Epub 2023 Dec 7.
2
Genetic Underpinnings of the Transition From Alcohol Consumption to Alcohol Use Disorder: Shared and Unique Genetic Architectures in a Cross-Ancestry Sample.从饮酒到酒精使用障碍的转变的遗传基础:跨血统样本中的共享和独特遗传结构。
Am J Psychiatry. 2023 Aug 1;180(8):584-593. doi: 10.1176/appi.ajp.21090892. Epub 2023 Jun 7.
3
Racial and Ethnic Bias in the Diagnosis of Alcohol Use Disorder in Veterans.种族和民族偏见对退伍军人酒精使用障碍的诊断影响。
Am J Psychiatry. 2023 Jun 1;180(6):426-436. doi: 10.1176/appi.ajp.21111097. Epub 2023 May 3.
4
Genetic diversity fuels gene discovery for tobacco and alcohol use.遗传多样性为烟草和酒精使用的基因发现提供了动力。
Nature. 2022 Dec;612(7941):720-724. doi: 10.1038/s41586-022-05477-4. Epub 2022 Dec 7.
5
Genome-Wide Investigation of Maximum Habitual Alcohol Intake in US Veterans in Relation to Alcohol Consumption Traits and Alcohol Use Disorder.全基因组范围内调查美国退伍军人习惯性最大饮酒量与饮酒特征和酒精使用障碍的关系。
JAMA Netw Open. 2022 Oct 3;5(10):e2238880. doi: 10.1001/jamanetworkopen.2022.38880.
6
Item-Level Genome-Wide Association Study of the Alcohol Use Disorders Identification Test in Three Population-Based Cohorts.基于三个人群队列的酒精使用障碍识别测试的项目水平全基因组关联研究。
Am J Psychiatry. 2022 Jan;179(1):58-70. doi: 10.1176/appi.ajp.2020.20091390. Epub 2021 May 14.
7
The impact of removing former drinkers from genome-wide association studies of AUDIT-C.从 AUDIT-C 的全基因组关联研究中去除前饮酒者的影响。
Addiction. 2021 Nov;116(11):3044-3054. doi: 10.1111/add.15511. Epub 2021 May 6.
8
Genome-wide analyses of behavioural traits are subject to bias by misreports and longitudinal changes.全基因组行为特征分析易受到错误报告和纵向变化的影响而产生偏差。
Nat Commun. 2021 Jan 7;12(1):20211. doi: 10.1038/s41467-020-20237-6.
9
Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits.对 435563 个人的问题性饮酒进行全基因组荟萃分析,为生物学研究提供了新的见解,并揭示了其与其他特征之间的关系。
Nat Neurosci. 2020 Jul;23(7):809-818. doi: 10.1038/s41593-020-0643-5. Epub 2020 May 25.
10
Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations.在来自多个群体的 274424 个人中进行全基因组关联研究,以探讨饮酒和饮酒障碍。
Nat Commun. 2019 Apr 2;10(1):1499. doi: 10.1038/s41467-019-09480-8.

Alcohol Consumption and Alcohol Use Disorder: Exposing an Increasingly Shared Genetic Architecture.

作者信息

White Julie D, Bierut Laura J

机构信息

GenOmics and Translational Research Center, RTI International, Research Triangle Park, N.C. (White); Department of Psychiatry, Washington University School of Medicine, St. Louis (Bierut).

出版信息

Am J Psychiatry. 2023 Aug 1;180(8):530-532. doi: 10.1176/appi.ajp.20230456.

DOI:10.1176/appi.ajp.20230456
PMID:37525606
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10765608/
Abstract
摘要