Alghamdi Amer, Alghamdi Yousef S, Hanafi Hany, Karami Mohamed M, Khayyat Waleed, Hersi Reem M, Naaman Nada K
Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, SAU.
Department of Ophthalmology, East Jeddah Hospital, Jeddah, SAU.
Cureus. 2023 Jun 30;15(6):e41187. doi: 10.7759/cureus.41187. eCollection 2023 Jun.
Molluscum contagiosum (MC) is a common benign cutaneous viral infection. It can affect any part of the skin with a high propensity for facial skin, especially in human immunodeficiency virus (HIV) patients with low CD4 count. We report a case of a 16-year-old female patient who presented with a giant isolated right upper eyelid MC lesion that served as the first clinical indicator of her HIV infection and acquired immunodeficiency syndrome (AIDS). A final diagnosis of MC was made based on the history, clinical findings, and histopathological examination. Moreover, due to its vital location, large size, and atypical presentation, a surgical excision by simple unroofing and curettage was performed under local anesthesia to speed recovery, prevent corneal complications, and reduce transmission. Her follow-up visits showed satisfactory clinical and cosmetic outcomes. Patients presenting with giant atypical eyelid lesions must be thoroughly investigated for immunosuppressive states, especially HIV infection. MC can have atypical presentations in HIV patients. To our knowledge, this is one of a few cases in the literature reporting a giant isolated eyelid MC lesion leading to a diagnosis of HIV infection with AIDS.
传染性软疣（MC）是一种常见的良性皮肤病毒感染。它可累及皮肤的任何部位，面部皮肤受累的可能性很高，尤其是在CD4细胞计数低的人类免疫缺陷病毒（HIV）患者中。我们报告一例16岁女性患者，其右眼睑出现巨大孤立性MC病变，这是她感染HIV及获得性免疫缺陷综合征（AIDS）的首个临床指标。根据病史、临床表现和组织病理学检查最终确诊为MC。此外，由于其位置关键、病变较大且表现不典型，在局部麻醉下进行了单纯挑破和刮除的手术切除，以加速恢复、预防角膜并发症并减少传播。她的随访显示临床和美容效果均令人满意。出现巨大非典型眼睑病变的患者必须全面排查免疫抑制状态，尤其是HIV感染。MC在HIV患者中可能有非典型表现。据我们所知，这是文献中少数几例报告巨大孤立性眼睑MC病变导致HIV感染合并AIDS诊断的病例之一。
