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脑积水作为新型冠状病毒肺炎可能的神经系统并发症:一例报告及系统文献综述

Hydrocephalus as Possible Neurological Complication of COVID-19: A Case Report and Systematic Literature Review.

作者信息

Verrienti Giulio, Megliola Gianluigi, Colamaria Antonio, Condò Tommaso, Lozupone Emilio

机构信息

Department of Neurorehabilitation, Casa di Cura Villa Verde, Lecce, ITA.

Division of Neurosurgery, Riuniti Hospital, Foggia, ITA.

出版信息

Cureus. 2023 Jun 30;15(6):e41199. doi: 10.7759/cureus.41199. eCollection 2023 Jun.

Abstract

Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), typically affects the respiratory system but can also present with neurological manifestations. Although some cases of hydrocephalus related to COVID-19 infection have been reported, a clear association between these two entities is not universally recognized yet. Here, we report another interesting case of hydrocephalus in a 60-year-old man with a previous aneurysmal subarachnoid haemorrhage (aSAH) who tested positive for COVID-19. Secondly, we illustrate a systematic overview of the previously reported cases of hydrocephalus related to COVID-19 infection. Finally, in light of the literature, we discuss the supposed underlying mechanisms that could make the association between COVID-19 infection and hydrocephalus plausible.

摘要

2019冠状病毒病(COVID-19)由严重急性呼吸综合征冠状病毒2(SARS-CoV-2)引起,通常影响呼吸系统,但也可能出现神经学表现。尽管已有一些与COVID-19感染相关的脑积水病例报道,但这两者之间的明确关联尚未得到普遍认可。在此,我们报告另一例有趣的脑积水病例,患者为一名60岁男性,既往有动脉瘤性蛛网膜下腔出血(aSAH),COVID-19检测呈阳性。其次,我们对先前报道的与COVID-19感染相关的脑积水病例进行了系统概述。最后,根据文献,我们讨论了可能使COVID-19感染与脑积水之间存在关联的潜在机制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e116/10387289/233d88d8f625/cureus-0015-00000041199-i01.jpg

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