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脑积水作为新型冠状病毒肺炎可能的神经系统并发症:一例报告及系统文献综述

Hydrocephalus as Possible Neurological Complication of COVID-19: A Case Report and Systematic Literature Review.

作者信息

Verrienti Giulio, Megliola Gianluigi, Colamaria Antonio, Condò Tommaso, Lozupone Emilio

机构信息

Department of Neurorehabilitation, Casa di Cura Villa Verde, Lecce, ITA.

Division of Neurosurgery, Riuniti Hospital, Foggia, ITA.

出版信息

Cureus. 2023 Jun 30;15(6):e41199. doi: 10.7759/cureus.41199. eCollection 2023 Jun.

DOI:10.7759/cureus.41199
PMID:37525817
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10387289/
Abstract

Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), typically affects the respiratory system but can also present with neurological manifestations. Although some cases of hydrocephalus related to COVID-19 infection have been reported, a clear association between these two entities is not universally recognized yet. Here, we report another interesting case of hydrocephalus in a 60-year-old man with a previous aneurysmal subarachnoid haemorrhage (aSAH) who tested positive for COVID-19. Secondly, we illustrate a systematic overview of the previously reported cases of hydrocephalus related to COVID-19 infection. Finally, in light of the literature, we discuss the supposed underlying mechanisms that could make the association between COVID-19 infection and hydrocephalus plausible.

摘要

2019冠状病毒病(COVID-19)由严重急性呼吸综合征冠状病毒2(SARS-CoV-2)引起,通常影响呼吸系统,但也可能出现神经学表现。尽管已有一些与COVID-19感染相关的脑积水病例报道,但这两者之间的明确关联尚未得到普遍认可。在此,我们报告另一例有趣的脑积水病例,患者为一名60岁男性,既往有动脉瘤性蛛网膜下腔出血(aSAH),COVID-19检测呈阳性。其次,我们对先前报道的与COVID-19感染相关的脑积水病例进行了系统概述。最后,根据文献,我们讨论了可能使COVID-19感染与脑积水之间存在关联的潜在机制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e116/10387289/34c67c1c201a/cureus-0015-00000041199-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e116/10387289/233d88d8f625/cureus-0015-00000041199-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e116/10387289/e7c602b59d77/cureus-0015-00000041199-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e116/10387289/34c67c1c201a/cureus-0015-00000041199-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e116/10387289/233d88d8f625/cureus-0015-00000041199-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e116/10387289/e7c602b59d77/cureus-0015-00000041199-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e116/10387289/34c67c1c201a/cureus-0015-00000041199-i03.jpg

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本文引用的文献

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Hydrocephalus secondary to COVID-19 infection.新型冠状病毒肺炎感染继发的脑积水
QJM. 2023 Jul 28;116(7):559-562. doi: 10.1093/qjmed/hcad043.
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Hydrocephalus As Possible Prodromal Manifestation of COVID-19: A Report of Two Cases.脑积水作为新型冠状病毒肺炎可能的前驱表现:两例报告
Cureus. 2023 Jan 30;15(1):e34371. doi: 10.7759/cureus.34371. eCollection 2023 Jan.
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A Case Report of Normal Pressure Hydrocephalus Developing After COVID-19 Infection.1例新冠病毒感染后发生正常压力脑积水的病例报告
Cureus. 2023 Jan 13;15(1):e33753. doi: 10.7759/cureus.33753. eCollection 2023 Jan.
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Unusual Post-COVID-19 Presentation With Tetraventricular Hydrocephalus: A Case Report.新型冠状病毒肺炎后出现四脑室脑积水的罕见表现:一例报告
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Macrophages and Monocytes: "Trojan Horses" in COVID-19.巨噬细胞和单核细胞:COVID-19 中的“特洛伊木马”。
Viruses. 2021 Oct 28;13(11):2178. doi: 10.3390/v13112178.
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Low-Pressure Hydrocephalus in Spontaneous Angiogram-Negative Subarachnoid Hemorrhage Following COVID-19 Infection.新型冠状病毒肺炎感染后自发性血管造影阴性蛛网膜下腔出血中的低压性脑积水
Cureus. 2021 Jul 27;13(7):e16674. doi: 10.7759/cureus.16674. eCollection 2021 Jul.