School of Biosciences, University of Birmingham, Birmingham B15 2TT, UK.
Microbiology (Reading). 2023 Aug;169(8). doi: 10.1099/mic.0.001380.
The bacterial predator is a model for the wider phenomenon of bacteria:bacteria predation, and the specialization required to achieve a lifestyle dependent on prey consumption. is able to recognize, enter and ultimately consume fellow Gram-negative bacteria, killing these prey from within their periplasmic space, and lysing the host at the end of the cycle. The classic phenotype-driven characterization (and observation of predation) has benefitted from an increased focus on molecular mechanisms and fluorescence microscopy and tomography, revealing new features of several of the lifecycle stages. Herein we summarize a selection of these advances and describe likely areas for exploration that will push the field toward a more complete understanding of this fascinating 'two-cell' system.
细菌捕食者是细菌捕食这一更广泛现象的模型，也是实现依赖猎物消耗的生活方式所需的专业化的模型。它能够识别、进入并最终消耗革兰氏阴性菌，从它们的周质空间内杀死这些猎物，并在周期结束时裂解宿主。经典的表型驱动特征（和捕食观察）受益于对分子机制和荧光显微镜和断层扫描的更集中关注，揭示了几个生命周期阶段的新特征。在这里，我们总结了其中的一些进展，并描述了可能的探索领域，这些领域将推动该领域朝着更全面地理解这个迷人的“双细胞”系统迈进。
