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PEPPLOT,一种用于UWGCG序列分析软件包的蛋白质二级结构分析程序。

PEPPLOT, a protein secondary structure analysis program for the UWGCG sequence analysis software package.

作者信息

Gribskov M, Burgess R R, Devereux J

出版信息

Nucleic Acids Res. 1986 Jan 10;14(1):327-34. doi: 10.1093/nar/14.1.327.

DOI:10.1093/nar/14.1.327
PMID:3753771
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC339416/
Abstract

We describe a program for the analysis of protein secondary structure that operates with the Sequence Analysis Software Package of the University of Wisconsin Genetics Computer Group (UWGCG). The program produces both graphic and printed output. Structure prediction using the Chou and Fasman and Robson et al methods, and hydropathy analysis by the method of Kyte and Doolittle are included along with a simplified method of hydrophobic moment analysis. The power of the program is the coordinated presentation of many different kinds of structural information on the same plot.

摘要

我们描述了一个用于分析蛋白质二级结构的程序,该程序可与威斯康星大学遗传学计算机组(UWGCG)的序列分析软件包一起运行。该程序可生成图形和打印输出。其中包括使用Chou和Fasman以及Robson等人的方法进行的结构预测,以及使用Kyte和Doolittle方法进行的亲水性分析,还有一种简化的疏水矩分析方法。该程序的强大之处在于能够在同一张图上协调呈现多种不同类型的结构信息。

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Nucleic Acids Res. 1986 Jan 10;14(1):327-34. doi: 10.1093/nar/14.1.327.
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本文引用的文献

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The helical hydrophobic moment: a measure of the amphiphilicity of a helix.螺旋疏水矩:一种衡量螺旋两亲性的指标。
Nature. 1982 Sep 23;299(5881):371-4. doi: 10.1038/299371a0.
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A simple method for displaying the hydropathic character of a protein.一种展示蛋白质亲水性特征的简单方法。
J Mol Biol. 1982 May 5;157(1):105-32. doi: 10.1016/0022-2836(82)90515-0.
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The hydrophobic moment detects periodicity in protein hydrophobicity.疏水矩检测蛋白质疏水性的周期性。
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Prediction of protein antigenic determinants from amino acid sequences.从氨基酸序列预测蛋白质抗原决定簇。
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Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins.预测球状蛋白质二级结构的简单方法的准确性及影响分析
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