用于在核酸序列中搜索氨基酸模式的算法。
Algorithms for the search of amino acid patterns in nucleic acid sequences.
作者信息
Peltola H, Söderlund H, Ukkonen E
出版信息
Nucleic Acids Res. 1986 Jan 10;14(1):99-107. doi: 10.1093/nar/14.1.99.
Abstract
Some algorithms are described for the search of regions in a nucleic acid sequence that, when translated into amino acids, are homologous to a given amino acid pattern. All algorithms are modifications of the dynamic programming method for sequence comparison such that the translation of codons is taken into account. One of the algorithms has been implemented as a FORTRAN 77 program. The program operates on files that follow the format of the EMBL Nucleotide Sequence Data Library.
摘要
描述了一些用于在核酸序列中搜索区域的算法，这些区域在翻译成氨基酸后与给定的氨基酸模式同源。所有算法都是对序列比较的动态规划方法的修改，以便考虑密码子的翻译。其中一种算法已被实现为一个FORTRAN 77程序。该程序对遵循EMBL核苷酸序列数据库格式的文件进行操作。
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