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埃塞俄比亚西北部莱盖因特区一家新建治疗中心的皮肤利什曼病

Cutaneous leishmaniasis in a newly established treatment centre in the Lay Gayint district, Northwest Ethiopia.

作者信息

Yizengaw Endalew, Nibret Endalkachew, Yismaw Gizachew, Gashaw Bizuayehu, Tamiru Dessalegn, Munshea Abaineh, Takele Yegnasew, Müller Ingrid, Chapman Lloyd, Weller Richard, Cotton James A, Kropf Pascale

机构信息

Department of Medical Laboratory Science College of Medicine and Health Science Bahir Dar University Bahir Dar Ethiopia.

Institute of Biotechnology Bahir Dar University Bahir Dar Ethiopia.

出版信息

Skin Health Dis. 2023 Mar 17;3(4):e229. doi: 10.1002/ski2.229. eCollection 2023 Aug.


DOI:10.1002/ski2.229
PMID:37538321
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10395643/
Abstract

BACKGROUND: Cutaneous leishmaniasis (CL) is a neglected tropical disease that primarily affects the most vulnerable populations. In Ethiopia, where this study took place, CL is an important health problem, however, the incidence of CL is poorly monitored. OBJECTIVES: This study took place in a recently established CL treatment centre, at Nefas Mewcha Hospital, Lay Gayint. This area was considered to be endemic for CL, however, no cases of CL from Lay Gayint had previously been officially reported to the Amhara Regional Health Bureau. METHODS: Following a CL awareness campaign, a retrospective data review was performed of patients presenting to this centre between July 2019 and March 2021. Basic demographic and clinical data were collected by a nurse and recorded in the logbook of the CL treatment centre. RESULTS: Two hundred and one patients presented for diagnosis and treatment. The age of the patients ranged from 2 to 75 years and 63.2% were males. Most patients were between 10- and 19-years-old. The majority (79.1%) of the patients presented with localised cutaneous leishmaniasis and 20.9% with mucocutaneous leishmaniasis. 98% of the patients tested positive for parasites by microscopy. CONCLUSIONS: This work underpinned how CL is a major public health problem in the Lay Gayint district. It also shows that raising awareness about CL in the community and providing diagnosis and treatment encouraged patients to travel to seek diagnosis and treatment.

摘要

背景:皮肤利什曼病(CL)是一种被忽视的热带疾病,主要影响最脆弱的人群。在本研究开展的埃塞俄比亚,CL是一个重要的健康问题,然而,CL的发病率监测不足。 目的:本研究在莱盖因特内法斯·梅乌查医院一个新设立的CL治疗中心进行。该地区被认为是CL的流行区,然而,此前没有来自莱盖因特的CL病例正式报告给阿姆哈拉地区卫生局。 方法:在开展CL宣传活动后,对2019年7月至2021年3月期间到该中心就诊的患者进行了回顾性数据审查。基本人口统计学和临床数据由一名护士收集,并记录在CL治疗中心的日志中。 结果:201名患者前来诊断和治疗。患者年龄在2至75岁之间,63.2%为男性。大多数患者年龄在10至19岁之间。大多数(79.1%)患者表现为局限性皮肤利什曼病,20.9%表现为黏膜皮肤利什曼病。98%的患者通过显微镜检查寄生虫呈阳性。 结论:这项工作证实了CL在莱盖因特地区是一个主要的公共卫生问题。它还表明,在社区提高对CL的认识并提供诊断和治疗鼓励了患者前来寻求诊断和治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c65d/10395643/e297a9e0935e/SKI2-3-e229-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c65d/10395643/824aec2cecf6/SKI2-3-e229-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c65d/10395643/e297a9e0935e/SKI2-3-e229-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c65d/10395643/824aec2cecf6/SKI2-3-e229-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c65d/10395643/e297a9e0935e/SKI2-3-e229-g003.jpg

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[1]
Cutaneous leishmaniasis in a newly established treatment centre in the Lay Gayint district, Northwest Ethiopia.

Skin Health Dis. 2023-3-17

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引用本文的文献

[1]
Molecular epidemiology, distribution, and determinants of cutaneous leishmaniasis in Northeast Ethiopia.

Sci Rep. 2025-7-16

[2]
Self-Reporting Cutaneous Leishmaniasis Patients and Nutritional Status: A Study of the Host Factor in Remote Areas of Ethiopia.

Iran J Parasitol. 2025

[3]
Double-triangular flap for reconstruction of a circular skin defect in the central frontal region.

Dermatol Reports. 2025-2-6

[4]
Epidemiological and clinical profiles of cutaneous leishmaniasis cases in Amhara National Regional State, Northwest Ethiopia: a multicenter retrospective study.

Dermatol Reports. 2025-2-6

[5]
Demographic characteristics and clinical features of patients presenting with different forms of cutaneous leishmaniasis, in Lay Gayint, Northern Ethiopia.

PLoS Negl Trop Dis. 2024-8

[6]
Effects of cutaneous leishmaniasis on patients' quality of life.

BMC Infect Dis. 2024-6-18

本文引用的文献

[1]
Prevalence and Risk Factors of Human Leishmaniasis in Ethiopia: A Systematic Review and Meta-Analysis.

Infect Dis Ther. 2021-3

[2]
Cutaneous leishmaniasis in north-central Ethiopia: trend, clinical forms, geographic distribution, and determinants.

Trop Med Health. 2020-6-3

[3]
The Geographical Distribution of Cutaneous Leishmaniasis Causative Agents in Iran and Its Neighboring Countries, A Review.

Front Public Health. 2020-2-18

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Prevalence and environmental determinants of cutaneous leishmaniasis in rural communities in Tigray, northern Ethiopia.

PLoS Negl Trop Dis. 2019-9-26

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Cutaneous Leishmaniasis Due to .

EClinicalMedicine. 2019-1-8

[6]
Prevalence of Cutaneous Leishmaniasis in Western Highlands in Yemen.

J Trop Med. 2019-2-28

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The epidemiology of cutaneous leishmaniasis in Golestan Province, Iran: A cross-sectional study of 8-years.

Parasite Epidemiol Control. 2019-3-7

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Uncharted territory of the epidemiological burden of cutaneous leishmaniasis in sub-Saharan Africa-A systematic review.

PLoS Negl Trop Dis. 2018-10-25

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Lancet. 2018-8-17

[10]
Risk factors for cutaneous leishmaniasis in the rainforest of Bolivia: a cross-sectional study.

Trop Med Health. 2018-4-17

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