Adly Heba M, Saati Abdullah A, Obaid Majed S, Saleh Saleh A K
Community Medicine and Pilgrims Healthcare Department, College of Medicine, Umm Al-Qura University, Makkah 21955, Saudi Arabia.
Biochemistry Department, College of Medicine, Umm Al-Qura University, Makkah 21955, Saudi Arabia.
Foods. 2025 Mar 17;14(6):1013. doi: 10.3390/foods14061013.
The potential migration of chemical compounds from plastic food packaging poses significant health risks, necessitating continuous monitoring and enhanced safety protocols. This study aimed to investigate the migration of nine chemical groups, including alanine, acetic acid, cyano derivatives, urea, amines, amides, benzene derivatives, nitrites, and non-specified compounds, across different food categories. A total of 195 packaged food samples from eleven food categories were analyzed using Headspace Gas Chromatography-Mass Spectrometry (GC-MS) to identify and quantify chemical migrants. Statistical analysis revealed significant differences in migration levels among food categories ( < 0.05). Cheese, candies, and chips exhibited the highest concentrations of alanine (65.95 ± 0.6384 mg/kg), acetic acid (57.80 ± 0.6383 mg/kg), and benzene derivatives (59.96 ± 1.844 mg/kg), respectively, while frozen raw meat and seafood showed the lowest levels for most compounds. High benzene and nitrite concentrations in certain samples raised particular concern due to their carcinogenic and toxicological effects. Regression analysis confirmed that food matrix type is a strong predictor of migration levels for several compounds. The findings emphasize the urgent need for stricter regulation, improved analytical techniques, and the development of safer packaging materials to reduce chemical migration risks and protect public health.
塑料食品包装中化合物的潜在迁移带来了重大健康风险，因此需要持续监测并加强安全规程。本研究旨在调查九种化学类别（包括丙氨酸、乙酸、氰基衍生物、尿素、胺类、酰胺类、苯衍生物、亚硝酸盐和未明确的化合物）在不同食品类别中的迁移情况。使用顶空气相色谱 - 质谱联用仪（GC-MS）对来自十一个食品类别的总共195份包装食品样本进行了分析，以识别和量化化学迁移物。统计分析显示食品类别之间的迁移水平存在显著差异（<0.05）。奶酪、糖果和薯片分别呈现出最高浓度的丙氨酸（65.95±0.6384毫克/千克）、乙酸（57.80±0.6383毫克/千克）和苯衍生物（59.96±1.844毫克/千克），而冷冻生肉和海鲜在大多数化合物方面的含量最低。某些样本中高浓度的苯和亚硝酸盐因其致癌和毒理学效应而引发了特别关注。回归分析证实食品基质类型是几种化合物迁移水平的有力预测指标。研究结果强调迫切需要更严格的监管、改进的分析技术以及开发更安全的包装材料，以降低化学迁移风险并保护公众健康。
