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菝葜:对其植物学、民族药理学、植物化学、药理活性、实际和潜在应用的综述。

Smilax china L.: A review of its botany, ethnopharmacology, phytochemistry, pharmacological activities, actual and potential applications.

机构信息

Key Laboratory of Basic and Application Research of Beiyao (Heilongjiang University of Chinese Medicine), Ministry of Education, Heilongjiang University of Chinese Medicine, Harbin, 150000, China.

Key Laboratory of Basic and Application Research of Beiyao (Heilongjiang University of Chinese Medicine), Ministry of Education, Heilongjiang University of Chinese Medicine, Harbin, 150000, China.

出版信息

J Ethnopharmacol. 2024 Jan 10;318(Pt B):116992. doi: 10.1016/j.jep.2023.116992. Epub 2023 Aug 3.

DOI:10.1016/j.jep.2023.116992
PMID:37541403
Abstract

ETHNOPHARMACOLOGICAL RELEVANCE

Smilax china L., an extensively used traditional Chinese medicine, is known as Baqia in China. It has been used to treat various inflammatory disorders, particularly pelvic inflammation.

AIM OF THE REVIEW

The present paper aims to provide an up-to-date review at the advancements of the investigations on the ethnopharmacology, phytochemistry, pharmacological effect and actual and potential applications of S. china. Besides, the possible tendency and perspective for future research of this plant are discussed, as well.

MATERIALS AND METHODS

This article uses "Smilax china L." "S. china" as the keyword and collects relevant information on Smilax china L. plants through electronic searches (Elsevier, PubMed, ACS, CNKI, Google Scholar, Baidu Scholar, Web of Science), relevant books, and classic literature about Chinese herb.

RESULTS

134 chemical constituents, among which steroid saponins and flavonoids are the predominant groups, have been isolated and identified from S. china. S. china with its active compounds is possessed of wide-reaching biological activities, including anti-inflammatory, anti-cancer, anti-oxidant, detoxify nicotine, anti-diabetes, anti-obesity, anti-hyperuricaemia, anti-hypertension, promoting skin wound and barrier repair and anti-bacterial activity. Besides, S. china is also applied to other fields, such as food industry and detection technology.

CONCLUSIONS

Based on the review of the existing phytochemical studies on Smilax china L., the structural characterization of Smilax china L. extract can continue to be the focus of future research. Pharmacological studies in vitro and in vivo have demonstrated some of the traditional uses of Smilax china L. extract, while other traditional uses still need to be confirmed by research.

摘要

民族药理学相关性

菝葜,一种广泛应用于传统中药的植物,在中国被称为“菝葜”。它被用于治疗各种炎症性疾病,特别是盆腔炎。

目的综述

本文旨在提供菝葜植物在民族药理学、植物化学、药理作用及实际和潜在应用方面研究进展的最新综述。此外,还讨论了该植物未来研究的可能趋势和前景。

材料和方法

本文使用“菝葜”“菝葜”作为关键词,通过电子搜索(Elsevier、PubMed、ACS、CNKI、Google Scholar、百度学者、Web of Science)、相关书籍和经典中药文献收集有关菝葜植物的相关信息。

结果

从菝葜中分离鉴定出 134 种化学成分,其中甾体皂苷和黄酮类化合物是主要成分。具有广泛生物活性的菝葜及其活性化合物,包括抗炎、抗癌、抗氧化、解毒尼古丁、抗糖尿病、抗肥胖、抗高尿酸血症、抗高血压、促进皮肤伤口和屏障修复以及抗菌活性。此外,菝葜还应用于食品工业和检测技术等其他领域。

结论

基于对菝葜植物现有植物化学研究的综述,菝葜提取物的结构特征可以继续成为未来研究的重点。体外和体内药理学研究证实了菝葜提取物的一些传统用途,而其他传统用途仍需要研究证实。

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