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东北突尼斯的糖尿病和高血压患病率及危险因素呼吁采取有效行动。

Prevalence and risk factors of diabetes mellitus and hypertension in North East Tunisia calling for efficient and effective actions.

机构信息

Laboratory of Biomedical Genomics and Oncogenetics, Institut Pasteur de Tunis, 13, Place Pasteur, Belvédère Tunisie, B.P. 74, 1002, Tunis, Tunisia.

University of Tunis El Manar, Tunis, Tunisia.

出版信息

Sci Rep. 2023 Aug 5;13(1):12706. doi: 10.1038/s41598-023-39197-0.

DOI:10.1038/s41598-023-39197-0
PMID:37543635
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10404238/
Abstract

Diabetes and hypertension are a serious public health problem worldwide. In the last decades, prevalence of these two metabolic diseases has dramatically increased in the Middle East and North Africa region, especially in Tunisia. This study aimed to determine the prevalence of type 2 diabetes (T2D) and High Blood Pressure (HBP) in Zaghouan, a North-East region of Tunisia. To this end, an exploratory study with stratified random sampling of 420 participants has been carried out. Various data were collected. Blood samples and urine were drawn for biochemical assay. Then, all data were analyzed using the statistical R software. Results showed an alarming situation with an inter-regional difference in prevalence of obesity (50.0%, CI 95.0%), HBP (39.0%, CI 95.0%) and T2D (32.0%, CI 95.0%). This study allowed the discovery of 24, 17 and 2 new cases of T2D, HBP and T2D&HBP respectively. The association of some socio-economic factors and biochemical parameters with these chronic diseases has been highlighted. To conclude, the health situation in the governorate of Zaghouan requires urgent interventions to better manage the growing epidemic of non-communicable diseases (NCD) in the region. This study demonstrated the importance of engaging health policy makers in road mapping and implementing national NCD prevention programs.

摘要

糖尿病和高血压是全球范围内严重的公共卫生问题。在过去几十年中,这两种代谢性疾病在中东和北非地区(尤其是突尼斯)的患病率显著上升。本研究旨在确定突尼斯东北部扎古安地区 2 型糖尿病(T2D)和高血压(HBP)的患病率。为此,进行了一项具有分层随机抽样的 420 名参与者的探索性研究。收集了各种数据。采集血样和尿样进行生化分析。然后,使用统计 R 软件分析所有数据。结果显示出令人担忧的情况,肥胖(50.0%,95.0%置信区间)、HBP(39.0%,95.0%置信区间)和 T2D(32.0%,95.0%置信区间)的患病率存在区域间差异。本研究发现了 24、17 和 2 例新的 T2D、HBP 和 T2D&HBP 病例。还强调了一些社会经济因素和生化参数与这些慢性病之间的关联。总之,扎古安省的健康状况需要紧急干预,以更好地管理该地区不断增长的非传染性疾病(NCD)流行。本研究表明,让卫生政策制定者参与制定路线图和实施国家 NCD 预防计划非常重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75ea/10404238/f000064df512/41598_2023_39197_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75ea/10404238/fff78048111b/41598_2023_39197_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75ea/10404238/77203c239780/41598_2023_39197_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75ea/10404238/dc39b55c9fbb/41598_2023_39197_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75ea/10404238/f000064df512/41598_2023_39197_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75ea/10404238/fff78048111b/41598_2023_39197_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75ea/10404238/77203c239780/41598_2023_39197_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75ea/10404238/dc39b55c9fbb/41598_2023_39197_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75ea/10404238/f000064df512/41598_2023_39197_Fig4_HTML.jpg

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