Golestan Rheumatology Research Center, Golestan University of Medical Sciences, Gorgan, Iran.
Deputy of Public Health, Golestan University of Medical Sciences, Gorgan, Iran.
Arch Iran Med. 2023 Feb 1;26(2):62-68. doi: 10.34172/aim.2023.11.
This study was conducted to evaluate the epidemiological features of bone and soft cancers in the Golestan province, Northern Iran from 2004 to 2016.
This is a descriptive cross-sectional study. All patients with primary bone and soft tissue cancers between 2004 and 2016 were included. Data were obtained from Golestan population-based cancer registry (GPCR). We calculated age-standardized incidence rates (ASRs) and reported the rates per 100000 person-year. Estimated annual percent change (EAPC) was also calculated to assess temporal trends in incidence rates of these cancers.
The ASRs of bone cancers and soft tissue cancers were 1.33 and 1.43 per 100000 person-year, respectively. This study also showed that the ASR of bone cancer was higher in men (1.51) than women (1.15). The ASR of soft tissue cancers in the urban population (1.58) was higher than rural (1.27), and was lower in women (1.37) than men (1.49). Two peaks were seen in the incidence of bone cancer. The first peak was in the age group of 10 to 20 years and the second was in patients over 60. We did not find significant temporal trends in the incidence of bone (EAPC=-1.14; >0.05) and soft tissue cancers (EAPC=-2.73; >0.05) during the study period.
Epidemiological features of bone and soft tissue cancers including gender, age and place of residence should be considered by health policy makers in designing cancer control programs.
本研究旨在评估 2004 年至 2016 年伊朗北部戈勒斯坦省骨和软组织癌症的流行病学特征。
这是一项描述性的横断面研究。所有 2004 年至 2016 年期间患有原发性骨和软组织癌症的患者均纳入研究。数据来自戈勒斯坦人群癌症登记处（GPCR）。我们计算了年龄标准化发病率（ASR），并报告了每 100000 人年的发病率。还计算了估计的年百分变化（EAPC），以评估这些癌症发病率的时间趋势。
骨癌和软组织癌的 ASR 分别为 1.33 和 1.43/100000 人年。本研究还表明，男性骨癌的 ASR（1.51）高于女性（1.15）。城市人口的软组织癌 ASR（1.58）高于农村（1.27），女性（1.37）低于男性（1.49）。骨癌的发病率有两个高峰。第一个高峰在 10 至 20 岁年龄组，第二个高峰在 60 岁以上患者中。在研究期间，我们未发现骨癌（EAPC=-1.14；>0.05）和软组织癌（EAPC=-2.73；>0.05）发病率的显著时间趋势。
卫生政策制定者在制定癌症控制计划时应考虑骨和软组织癌症的流行病学特征，包括性别、年龄和居住地。
