Cancer Research Center, Golestan University of Medical Sciences, Gorgan, Iran.
Deputy of Public Health, Golestan University of Medical Sciences, Gorgan, Iran.
Arch Iran Med. 2021 Jan 1;24(1):1-6. doi: 10.34172/aim.2021.01.
Thyroid cancer is the most common type of endocrine cancer. We aimed to determine the incidence rates of thyroid cancer across a 10-year period (2004-2013) in Golestan, Iran.
We obtained the thyroid cancer data from Golestan Population-Based Cancer Registry (GPCR). Age-standardized incidence rates (ASR) were calculated and reported per 100000 person-years. The Joinpoint software was used to assess time trends, and average annual percent changes (AAPCs) and their corresponding 95% confidence intervals (CIs) were reported.
Of 326 registered patients, 83 (25.5%) were men and 243 (74.5%) were women. The mean age was 51.3 and 42.6 years for males and females, respectively. Overall, the ASR of thyroid cancer was 2.2 per 100000 person-year (AAPC = 2.76; 95% CI: -3.68 to 9.64). The test of co-incidence showed a statistically significant difference in the incidence of thyroid cancer between men (1.3) and women (3.2) (P < 0.001). According to our results, the ASR of thyroid cancer in western parts of Golestan is higher, including Gorgan and Aliabad cities.
Increasing trends in incidence rates of thyroid cancer were found in the Golestan province during the study period, especially in women. We found significantly higher rates of thyroid cancer in women. Geographical diversities were seen in incidence rates of thyroid cancer in the Golestan province. Our results may be helpful for designing further researches to investigate the epidemiological aspects of thyroid cancer in the Golestan province.
甲状腺癌是最常见的内分泌系统癌症。本研究旨在确定伊朗戈勒斯坦省在 10 年间（2004-2013 年）甲状腺癌的发病率。
我们从戈勒斯坦人群癌症登记处（GPCR）获得了甲状腺癌的数据。按每 10 万人年计算年龄标准化发病率（ASR），并进行报告。使用 Joinpoint 软件评估时间趋势，报告平均年变化百分比（AAPC）及其相应的 95%置信区间（CI）。
在登记的 326 名患者中，83 名（25.5%）为男性，243 名（74.5%）为女性。男性和女性的平均年龄分别为 51.3 岁和 42.6 岁。总体而言，甲状腺癌的 ASR 为 2.2/10 万人年（AAPC=2.76；95%CI：-3.68 至 9.64）。共同发生率检验表明，男性（1.3）和女性（3.2）甲状腺癌发病率存在统计学差异（P<0.001）。根据我们的结果，戈勒斯坦西部地区（包括戈尔甘和阿里阿巴德市）的甲状腺癌 ASR 较高。
在研究期间，戈勒斯坦省甲状腺癌的发病率呈上升趋势，尤其是在女性中。我们发现女性甲状腺癌的发病率显著较高。戈勒斯坦省甲状腺癌的发病率存在地理差异。我们的研究结果可能有助于设计进一步的研究，以调查戈勒斯坦省甲状腺癌的流行病学特征。
