Kumar Munish, Singla Robin, Singh Gagandeep, Kasrija Rishabh, Sharma Manish
Department of Oral Surgery, Guru Nanak Dev Dental College, Sunam, IND.
Department of Oral Surgery, JSS Dental College, Mysuru, IND.
Cureus. 2023 Jul 6;15(7):e41465. doi: 10.7759/cureus.41465. eCollection 2023 Jul.
Parry-Romberg syndrome (PRS) is a rare degenerative disorder of unknown cause that causes slow, progressive atrophy on one side of the face. The cause may be a malfunction of the sympathetic nervous system, with or without neurological symptoms. Atrophy usually begins in childhood and progresses gradually over several years. Stabilization can take up to 20 years. There is no definitive cure for this condition, but once the condition is stabilized, reconstructive surgery of the damaged skin and soft tissue can correct the deformity. The objective of this article is to present an insight into the etiology of PRS with a case report of a 15-year-old male patient, who was diagnosed with PRS due to trauma and developed progressive hemifacial atrophy without neurological manifestations. PRS is a progressive disease that severely affects one side of the face. Because of its devastating effects on the entire body, treatment requires a multidisciplinary approach. Further research is needed to clearly understand the etiology and provide patients with accurate treatment plans.
帕里-罗姆伯格综合征（PRS）是一种病因不明的罕见退行性疾病，可导致面部一侧缓慢、进行性萎缩。病因可能是交感神经系统功能失调，伴有或不伴有神经症状。萎缩通常始于儿童期，并在数年中逐渐进展。病情稳定可能需要长达20年的时间。这种疾病尚无确切的治愈方法，但一旦病情稳定，对受损皮肤和软组织进行重建手术可以矫正畸形。本文的目的是通过一名15岁男性患者的病例报告，深入了解PRS的病因，该患者因创伤被诊断为PRS，并出现了无神经表现的进行性半侧面部萎缩。PRS是一种严重影响面部一侧的进行性疾病。由于其对全身的破坏性影响，治疗需要多学科方法。需要进一步研究以清楚了解病因，并为患者提供准确的治疗方案。
