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一种用于抵御污染物和呼吸道传染因子的新型鼻内空气动力学过滤技术:颗粒过滤效能评估

A new aerodynamic endonasal filtration technology for protection against pollutants and respiratory infectious agents: evaluation of the particle filtration efficacy.

作者信息

Saravanan Padmanabhan, Broccolo Francesco, Ali Nurshahidah, Toh Alden, Mulyana Sakinah, Beng Goh Lay, Imperi Enrico, Picano Alfredo

机构信息

School of Applied Science, Temasek Polytechnic, Singapore, Singapore.

Department of Biological and Environmental Sciences and Technologies (DiSTeBA), University of Salento, Lecce, Italy.

出版信息

Front Med Technol. 2023 Jul 21;5:1219996. doi: 10.3389/fmedt.2023.1219996. eCollection 2023.

Abstract

An innovative nasal filter was tested, based on aerodynamic air filtration and not on conventional air filtration by means of mesh filters. A custom testing system was designed and three sizes of the filter have been tested vs. monodispersed SiO particles sized 5 μm, 1 μm, and 0.5 μm under cycling flow of 6 liters per minute, provided by an artificial lung breather simulating spontaneous breathing. Accelerated testing was implemented, challenging filters with a maximum load of 200 mg per cubic meter. All three filters' sizes showed initial filtration efficiencies above 90% vs. all particles' sizes, decreased to not less than 80% after 30 min of accelerated testing, corresponding to 4.5 days of continuous use at 2 mg challenge, this value being associated with hazardous air conditions in the PSI scale. Results in this study indicate that nasal filters based on aerodynamic air filtration can provide fine and ultrafine filtration, offering protection in day-to-day life from risks associated with pollens, mites, PM, pollutants, and respiratory infectious agents, introducing acceptable respiratory resistance.

摘要

一种创新的鼻过滤器进行了测试,其基于空气动力学空气过滤,而非通过网状过滤器进行传统的空气过滤。设计了一个定制测试系统,并在由模拟自主呼吸的人工肺呼吸器提供的每分钟6升循环气流下,对三种尺寸的过滤器针对粒径为5微米、1微米和0.5微米的单分散SiO颗粒进行了测试。实施了加速测试,以每立方米200毫克的最大负载对过滤器进行挑战。所有三种尺寸的过滤器对所有粒径颗粒的初始过滤效率均高于90%,在加速测试30分钟后降至不低于80%,这相当于在2毫克挑战下连续使用4.5天,该值与PSI量表中的有害空气状况相关。本研究结果表明,基于空气动力学空气过滤的鼻过滤器可提供精细和超细过滤,在日常生活中为抵御与花粉、螨虫、颗粒物、污染物和呼吸道传染因子相关的风险提供保护,并引入可接受的呼吸阻力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc9d/10401429/1f0cd245c9f4/fmedt-05-1219996-g001.jpg

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