Goliński P, Wnuk S, Chełkowski J, Visconti A, Schollenberger M
Appl Environ Microbiol. 1986 Apr;51(4):743-5. doi: 10.1128/aem.51.4.743-745.1986.
A compound very similar to the mycotoxin citrinin was observed on thin-layer chromatographic plates during the screening analysis of grain extracts. This compound was produced by 22 of the tested Fusarium avenaceum (Corda ex Fries) Sacc. strains isolated from wheat, triticale, barley, corn, and potatoes. A chemical test confirmed the presence of an unknown compound, which was given the preliminary name of antibiotic Y (indicating yellow fluorescence). The following properties of the new metabolite are described: spectroscopic (UV, infrared, proton nuclear magnetic resonance, fluorescence, and mass spectrometry), phytotoxic, antibiotic (inhibitory effect of bacterial growth), and toxic (toxicity to Artemia salina, chicken embryos, and mouse fibroblasts). Elemental analysis of the compound showed that it had the general formula C15H10O8, in agreement with the mass spectrometric finding that the molecular ion had a molecular weight of 318. The structure of the compound is presently under study.
在谷物提取物的筛选分析过程中，在薄层色谱板上观察到一种与霉菌毒素桔霉素非常相似的化合物。该化合物由从小麦、小黑麦、大麦、玉米和土豆中分离出的22株供试燕麦镰刀菌（Corda ex Fries）Sacc.菌株产生。化学测试证实了一种未知化合物的存在，该化合物被初步命名为抗生素Y（表明黄色荧光）。描述了这种新代谢物的以下特性：光谱特性（紫外、红外、质子核磁共振、荧光和质谱）、植物毒性、抗生素特性（对细菌生长的抑制作用）和毒性（对卤虫、鸡胚和小鼠成纤维细胞的毒性）。该化合物的元素分析表明其通式为C15H10O8，这与质谱分析结果一致，即分子离子的分子量为318。该化合物的结构目前正在研究中。
