Zhang Xiangyuan, Yuan Yinfang
Critical Care Medicine, Shaoyang University Affiliated Second Hospital, Shaoyang, China.
Nephrology Department, Shaoyang University Affiliated Second Hospital, Shaoyang, China.
Front Pharmacol. 2023 Jul 21;14:1122778. doi: 10.3389/fphar.2023.1122778. eCollection 2023.
Hyperkalemia, metabolic acidosis, and acute uremia are the main symptoms in patients with severe acute renal failure (SARF). Its clinical symptoms are obvious, and it is extremely harmful. It needs to take active and effective measures for treatment. CRRT refers to any extracorporeal blood purification treatment technique designed to replace impaired renal function for 24 h or nearly 24 h. Hemodialysis treatment is a treatment process in which the patient's blood is discharged from the body, passes through the dialysis membrane and dialysis machine, removes excess toxins and water in the body, corrects electrolyte and acid-base disorders, and then returns the blood to the body. In order to explore the efficacy of replacement therapy and hemodialysis in the treatment of severe acute renal failure, the data samples were randomly divided into observation group and control group, who were given conventional treatment, hemodialysis and replacement therapy, respectively. Clinical data show that after replacement therapy and hemodialysis in patients with severe acute renal failure in the observation group, the levels of parathyroid hormone, renin, and quality of life were all improved, with an improvement rate of 9.47%, which has certain promotional value.
高钾血症、代谢性酸中毒和急性尿毒症是重症急性肾衰竭（SARF）患者的主要症状。其临床症状明显，危害极大。需要采取积极有效的措施进行治疗。连续性肾脏替代治疗（CRRT）是指任何旨在替代受损肾功能达24小时或接近24小时的体外血液净化治疗技术。血液透析治疗是一个将患者血液引出体外，通过透析膜和透析机，清除体内多余毒素和水分，纠正电解质及酸碱紊乱，然后将血液回输体内的治疗过程。为探讨替代治疗和血液透析在重症急性肾衰竭治疗中的疗效，将数据样本随机分为观察组和对照组，分别给予常规治疗、血液透析和替代治疗。临床数据显示，观察组重症急性肾衰竭患者经替代治疗和血液透析后，甲状旁腺激素、肾素水平及生活质量均有所改善，改善率为9.47%，具有一定的推广价值。
