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在无法测量直肠温度时,用于劳力性热射病现场治疗的推荐水浸持续时间。

Recommended water immersion duration for the field treatment of exertional heat stroke when rectal temperature is unavailable.

作者信息

Flouris Andreas D, Notley Sean R, Stearns Rebecca L, Casa Douglas J, Kenny Glen P

机构信息

FAME Laboratory, Department of Physical Education and Sport Science, University of Thessaly, Trikala, Greece.

Human and Environmental Physiology Research Unit, Faculty of Health Sciences, University of Ottawa, Ottawa, ON, Canada.

出版信息

Eur J Appl Physiol. 2024 Feb;124(2):479-490. doi: 10.1007/s00421-023-05290-5. Epub 2023 Aug 8.

Abstract

INTRODUCTION

The recommended treatment for exertional heat stroke is immediate, whole-body immersion in < 10 °C water until rectal temperature (T) reaches ≤ 38.6 °C. However, real-time T assessment is not always feasible or available in field settings or emergency situations. We defined and validated immersion durations for water temperatures of 2-26 °C for treating exertional heat stroke.

METHODS

We compiled data for 54 men and 18 women from 7 previous laboratory studies and derived immersion durations for reaching 38.6 °C T. The resulting immersion durations were validated against the durations of cold-water immersion used to treat 162 (98 men; 64 women) exertional heat stroke cases at the Falmouth Road Race between 1984 and 2011.

RESULTS

Age, height, weight, body surface area, body fat, fat mass, lean body mass, and peak oxygen uptake were weakly associated with the cooling time to a safe T of 38.6 °C during immersions to 2-26 °C water (R range: 0.00-0.16). Using a specificity criterion of 0.9, receiver operating characteristics curve analysis showed that exertional heat stroke patients must be immersed for 11-12 min when water temperature is ≤ 9 °C, and for 18-19 min when water temperature is 10-26 °C (Cohen's Kappa: 0.32-0.75, p < 0.001; diagnostic odds ratio: 8.63-103.27).

CONCLUSION

The reported immersion durations are effective for > 90% of exertional heat stroke patients with pre-immersion T of 39.5-42.8 °C. When available, real-time T monitoring is the standard of care to accurately diagnose and treat exertional heat stroke, avoiding adverse health outcomes associated with under- or over-cooling, and for implementing cool-first transport second exertional heat stroke policies.

摘要

引言

劳力性热射病的推荐治疗方法是立即将全身浸入温度低于10°C的水中,直至直肠温度(T)降至≤38.6°C。然而,在现场环境或紧急情况下,实时体温评估并不总是可行或可用的。我们定义并验证了2至26°C水温下治疗劳力性热射病的浸泡时间。

方法

我们汇总了之前7项实验室研究中54名男性和18名女性的数据,并得出了达到38.6°C体温所需的浸泡时间。将得出的浸泡时间与1984年至2011年法尔茅斯路跑比赛中用于治疗162例(98名男性;64名女性)劳力性热射病病例的冷水浸泡时间进行了验证。

结果

年龄、身高、体重、体表面积、体脂、脂肪量、去脂体重和最大摄氧量与在2至26°C水温浸泡期间冷却至安全体温38.6°C的时间弱相关(R范围:0.00 - 0.16)。使用0.9的特异性标准,受试者工作特征曲线分析表明,当水温≤9°C时,劳力性热射病患者必须浸泡11 - 12分钟;当水温为10 - 26°C时,必须浸泡18 - 19分钟(科恩卡方值:0.32 - 0.75,p < 0.001;诊断比值比:8.63 - 103.27)。

结论

对于90%以上浸泡前体温为39.5至42.8°C的劳力性热射病患者,报告的浸泡时间是有效的。如果可行,实时体温监测是准确诊断和治疗劳力性热射病的标准治疗方法,可避免与冷却不足或过度冷却相关的不良健康后果,并用于实施先冷却后转运的劳力性热射病治疗策略。

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