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纳米酶的应用及其在缺血性脑卒中治疗中的进展。

Application of Nanozymes and its Progress in the Treatment of Ischemic Stroke.

机构信息

School of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, 250355, Shandong, China.

Second Affiliated Hospital, Shandong First Medical University & Shandong Academy of Medical Sciences, Taian, 271000, Shandong, China.

出版信息

Transl Stroke Res. 2024 Oct;15(5):880-892. doi: 10.1007/s12975-023-01182-0. Epub 2023 Aug 9.

Abstract

Nanozymes are a new kind of material which has been applied since the beginning of this century, and its birth has promoted the development of chemistry, materials science, and biology. Nanozymes can be used as a substitute for natural enzyme and has a wide range of applications; therefore, it has attracted extensive attention from all sectors of the community, and the number of studies has constantly increasing. In this paper, we introduced the outstanding achievements in the field of nanozymes in recent years from the main function, the construction of nanozyme-based biosensors, and the treatment of ischemic stroke, and we also illustrated the internal mechanism and the catalytic principle. In the end, the obstacles and challenges in the future development of nanozymes were proposed.

摘要

纳米酶是本世纪初开始应用的一种新型材料,它的诞生推动了化学、材料科学和生物学的发展。纳米酶可以作为天然酶的替代品,具有广泛的应用前景,因此引起了社会各界的广泛关注,研究数量不断增加。本文从主要功能、基于纳米酶的生物传感器构建和缺血性脑卒中治疗等方面介绍了近年来纳米酶领域的突出成果,并阐述了其内在机制和催化原理。最后提出了纳米酶未来发展所面临的障碍和挑战。

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