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探索尺寸变异性对作为光学造影剂的上转换纳米颗粒效率的影响。

Exploring the Effect of Size Variability on Efficiency of Upconversion Nanoparticles as Optical Contrast Agents.

作者信息

Banerjee Abhishek, Shwetabh Kumar, Kumar Kaushal, Poddar Raju

机构信息

Biophotonics Lab, Department of Bioengineering and Biotechnology, Birla Institute of Technology, Mesra, Ranchi, Jharkhand, 835215, India.

Optical Materials and Bio-Imaging Research Laboratory, Department of Physics, Indian Institute of Technology (Indian School of Mines), Dhanbad, 826004, India.

出版信息

J Fluoresc. 2024 Jul;34(4):1589-1602. doi: 10.1007/s10895-023-03375-0. Epub 2023 Aug 10.

DOI:10.1007/s10895-023-03375-0
PMID:37561366
Abstract

The current works explores the optical contrast property and nanaotheranostic capabilities of the rare earth based Upconversion nanoparticles. Optical coherence tomography (OCT) has been used to explore the particles ability to increase contrast and improve signal intensity. Photo thermal OCT, a function extension of OCT has been used to gauge the photo thermal potential of the nanoparticles. The nanoparticles successfully improved contrast and information from the deeper layers of the sample. The particles also showed excellent capability for use as photo thermal agents.

摘要

当前的研究探索了基于稀土的上转换纳米颗粒的光学对比度特性和纳米诊疗能力。光学相干断层扫描(OCT)已被用于探究这些颗粒增强对比度和提高信号强度的能力。光热OCT作为OCT的功能扩展,已被用于评估纳米颗粒的光热潜力。这些纳米颗粒成功地提高了样本深层的对比度和信息。这些颗粒还显示出作为光热剂的优异能力。

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J Fluoresc. 2024 Jul;34(4):1589-1602. doi: 10.1007/s10895-023-03375-0. Epub 2023 Aug 10.
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引用本文的文献

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Materials (Basel). 2024 Feb 11;17(4):854. doi: 10.3390/ma17040854.

本文引用的文献

1
Investigation of GdO: Er/Yb Upconversion Nanoparticles (UCNPs) as a Multi-model Contrast Agent for Functional Optical Coherence Tomography (fOCT).研究 GdO: Er/Yb 上转换纳米粒子 (UCNPs) 作为多功能光学相干断层扫描 (fOCT) 的造影剂。
J Fluoresc. 2021 Mar;31(2):541-550. doi: 10.1007/s10895-021-02681-9. Epub 2021 Jan 16.
2
Ex-vivo molecular imaging with upconversion nanoparticles (UCNPs) using photo thermal optical coherence tomography (PTOCT).基于上转换纳米粒子(UCNPs)的光热光学相干断层扫描(PTOCT)的离体分子成像。
Photodiagnosis Photodyn Ther. 2021 Mar;33:102027. doi: 10.1016/j.pdpdt.2020.102027. Epub 2020 Sep 24.
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用于生物成像的上转换近红外光子
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Upconverting nanoparticles: a versatile platform for wide-field two-photon microscopy and multi-modal in vivo imaging.上转换纳米粒子:一种用于宽场双光子显微镜和多模态体内成像的多功能平台。
Chem Soc Rev. 2015 Mar 21;44(6):1302-17. doi: 10.1039/c4cs00173g.
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Lanthanide-doped upconverting luminescent nanoparticle platforms for optical imaging-guided drug delivery and therapy.镧系掺杂上转换发光纳米颗粒平台用于光学成像引导的药物输送和治疗。
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