Fazeli Seyed Amirhossein, Alirezaei Amirhesam, Miladipour Amirhossein, Salarabedi Mohammad-Mahdi, Karimi Toudeshki Kimia
Department of Nephrology, Clinical Research and Development Center at Shahid Modarres Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Student Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Adv Biomed Res. 2023 Jun 28;12:152. doi: 10.4103/abr.abr_167_22. eCollection 2023.
The world has experienced a global medical and socioeconomic burden following the coronavirus disease 2019 (COVID-19) pandemic. COVID-19 is a systemic disease and may affect different organs including the kidneys. Current literature contains reports on COVID-19-related conditions such as acute kidney injury, and complications experienced by chronic kidney disease, end stage kidney disease, and kidney transplant patients. Here, we discuss the incidence of kidney allograft rejection, immunosuppression management and rejection risk, donor-specific antibodies and previous rejection episodes, and rejection outcomes in kidney transplant recipients with COVID-19 by reviewing current studies.
2019年冠状病毒病(COVID-19)大流行给全球带来了医疗和社会经济负担。COVID-19是一种全身性疾病,可能会影响包括肾脏在内的不同器官。目前的文献中有关于COVID-19相关病症的报道,如急性肾损伤,以及慢性肾脏病、终末期肾病和肾移植患者所经历的并发症。在此,我们通过回顾当前研究,探讨了COVID-19肾移植受者中肾移植排斥反应的发生率、免疫抑制管理和排斥风险、供体特异性抗体和既往排斥反应发作情况,以及排斥反应结局。