Mostafa Shaimaa F, Eid Gehan M
Department of Anesthesia, Surgical Intensive Care and Pain Medicine, Faculty of Medicine, Tanta University, Egypt.
J Anaesthesiol Clin Pharmacol. 2023 Apr-Jun;39(2):250-257. doi: 10.4103/joacp.joacp_416_21. Epub 2022 Feb 10.
Pain contributes to flail chest morbidities. The aim of this study was to compare the analgesic effects of ultrasound-guided erector spinae plane block (ESPB) with thoracic epidural analgesia (TEA) in patients with traumatic flail chest.
Sixty patients aged 18 - 60 years, ASA I-II, with unilateral flail chest were allocated into TEA group with a loading dose of 6 ml bupivacaine 0.25% and 2 μg/ml fentanyl and ESPB group with a loading dose of 20 ml bupivacaine 0.25% and 2 μg/ml fentanyl. This was followed by continuous infusion of 6 ml/hour bupivacaine 0.125% and 2 μg/ml fentanyl in both groups for 4 days. Pain scores at rest and on coughing, rescue analgesic consumption, PaO/FIO ratio, PaCO, pulmonary functions and adverse events were recorded.
In both groups, Visual Analog Scale (VAS) scores at rest and on coughing were significantly decreased after block initiation as compared to pre-block value. At all-time points, VAS scores at rest and on coughing were insignificantly different between both groups. PaO/FIO ratio, forced vital capacity (FVC) and forced expiratory volume in 1 second (FEV1) were significantly increased and respiratory rate, PaCO, were significantly decreased as compared to pre-block values of the same group without significant difference between both groups. The incidence of hypotension was significantly higher in TEA group than ESPB group.
ESPB can achieve adequate analgesia in traumatic flail chest equivalent to that of TEA with significant improvement of arterial oxygenation and pulmonary functions and without serious adverse effects.
疼痛会导致连枷胸的并发症。本研究旨在比较超声引导下竖脊肌平面阻滞(ESPB)与胸椎硬膜外镇痛(TEA)对创伤性连枷胸患者的镇痛效果。
将60例年龄在18 - 60岁、美国麻醉医师协会(ASA)分级为I-II级的单侧连枷胸患者分为TEA组,给予负荷剂量0.25%布比卡因6 ml和2 μg/ml芬太尼;ESPB组,给予负荷剂量0.25%布比卡因20 ml和2 μg/ml芬太尼。随后两组均持续输注0.125%布比卡因6 ml/小时和2 μg/ml芬太尼,持续4天。记录静息和咳嗽时的疼痛评分、补救性镇痛药物用量、动脉血氧分压/吸入氧浓度(PaO₂/FiO₂)比值、动脉血二氧化碳分压(PaCO₂)、肺功能及不良事件。
与阻滞前相比,两组在阻滞开始后静息和咳嗽时的视觉模拟评分(VAS)均显著降低。在所有时间点,两组静息和咳嗽时的VAS评分无显著差异。与同组阻滞前相比,两组的PaO₂/FiO₂比值、用力肺活量(FVC)和第1秒用力呼气量(FEV₁)均显著升高,呼吸频率、PaCO₂均显著降低,两组间无显著差异。TEA组低血压的发生率显著高于ESPB组。
ESPB在创伤性连枷胸中可实现与TEA相当的充分镇痛,能显著改善动脉氧合和肺功能,且无严重不良反应。