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肋骨骨折的镇痛:叙述性综述。

Analgesia for rib fractures: a narrative review.

机构信息

Department of Anesthesiology and Perioperative Medicine, Queen's University, Kingston, ON, Canada.

Department of Public Health Sciences (Epidemiology), School of Medicine, Queen's University, Kingston, ON, Canada.

出版信息

Can J Anaesth. 2024 Apr;71(4):535-547. doi: 10.1007/s12630-024-02725-1. Epub 2024 Mar 8.

Abstract

PURPOSE

Rib fracture(s) is a common and painful injury often associated with significant morbidity (e.g., respiratory complications) and high mortality rates, especially in the elderly. Risk stratification and prompt implementation of analgesic pathways using a multimodal analgesia approach comprise a primary endpoint of care to reduce morbidity and mortality associated with rib fractures. This narrative review aims to describe the most recent evidence and care pathways currently available, including risk stratification tools and pharmacologic and regional analgesic blocks frequently used as part of the broadly recommended multimodal analgesic approach.

SOURCE

Available literature was searched using PubMed and Embase databases for each topic addressed herein and reviewed by content experts.

PRINCIPAL FINDINGS

Four risk stratification tools were identified, with the Study of the Management of Blunt Chest Wall Trauma score as most predictive. Current evidence on pharmacologic (i.e., acetaminophen, nonsteroidal anti-inflammatory drugs, gabapentinoids, ketamine, lidocaine, and dexmedetomidine) and regional analgesia (i.e., thoracic epidural analgesia, thoracic paravertebral block, erector spinae plane block, and serratus anterior plane block) techniques was reviewed, as was the pathophysiology of rib fracture(s) and its associated complications, including the development of chronic pain and disabilities.

CONCLUSION

Rib fracture(s) continues to be a serious diagnosis, with high rates of mortality, development of chronic pain, and disability. A multidisciplinary approach to management, combined with appropriate analgesia and adherence to care bundles/protocols, has been shown to decrease morbidity and mortality. Most of the risk-stratifying care pathways identified perform poorly in predicting mortality and complications after rib fracture(s).

摘要

目的

肋骨骨折是一种常见且疼痛的损伤,常伴有较高的发病率(例如,呼吸并发症)和死亡率,尤其是在老年人中。风险分层和通过多模式镇痛方法及时实施镇痛途径是降低与肋骨骨折相关的发病率和死亡率的主要护理目标。本叙述性综述旨在描述最新的证据和当前可用的护理途径,包括风险分层工具以及经常作为广泛推荐的多模式镇痛方法一部分使用的药物和区域镇痛阻滞。

资料来源

使用 PubMed 和 Embase 数据库搜索了与本文所讨论的每个主题相关的可用文献,并由内容专家进行了审查。

主要发现

确定了四种风险分层工具,其中以钝性胸部创伤管理研究评分最具预测性。对药物(即,对乙酰氨基酚、非甾体抗炎药、加巴喷丁类、氯胺酮、利多卡因和右美托咪定)和区域镇痛(即,胸椎硬膜外镇痛、胸椎旁神经阻滞、竖脊肌平面阻滞和前锯肌平面阻滞)技术的当前证据进行了回顾,以及肋骨骨折的病理生理学及其相关并发症,包括慢性疼痛和残疾的发展。

结论

肋骨骨折仍然是一种严重的诊断,死亡率高,慢性疼痛和残疾的发生率高。管理的多学科方法,结合适当的镇痛和遵守护理包/方案,已被证明可降低发病率和死亡率。确定的大多数风险分层护理途径在预测肋骨骨折后的死亡率和并发症方面表现不佳。

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