Mayerich David, Wythe Joshua D
Department of Electrical and Computer Engineering, University of Houston, Houston, TX, USA.
Department of Integrative Physiology, Baylor College of Medicine, Houston, TX, USA.
Nat Cardiovasc Res. 2022 Aug;1(8):691-693. doi: 10.1038/s44161-022-00115-8. Epub 2022 Aug 12.
Collateral arteries may act as natural bypasses that reduce hypoperfusion after a coronary blockage. 3D imaging of neonatal and adult mouse hearts, plus human fetal and diseased adult hearts, is now used to computationally predict flow within the heart, and understand the cardioprotective role of collateral arteries in vivo.
侧支动脉可作为天然旁路,减少冠状动脉阻塞后的灌注不足。目前,利用新生小鼠和成年小鼠心脏以及人类胎儿和患病成年心脏的三维成像,通过计算预测心脏内的血流,并了解侧支动脉在体内的心脏保护作用。