Christie Jordan, Clements Mark A, Williams David D, Cernich Joseph, Patton Susana R
Division of Pediatric Endocrinology, Children's Mercy Hospitals and Clinics, Kansas City, MO, USA.
Biostatistics and Epidemiology, Children's Mercy Hospitals and Clinics, Kansas City, MO, USA.
J Diabetes Sci Technol. 2025 Mar;19(2):340-344. doi: 10.1177/19322968231192979. Epub 2023 Aug 11.
To meet their glycated hemoglobin (HbA1c) goals, youth with type 1 diabetes (T1D) need to engage with their daily T1D treatment. The mealtime insulin Bolus score (BOLUS) is an objective measure of youth's T1D engagement which we have previously shown to be superior to other objective engagement measures in predicting youth's HbA1c. Here, to further assess the BOLUS score's validity, we compared the strengths of the associations between youth's HbA1c with their mean insulin BOLUS score and a valid, self-report measure of T1D engagement, the Self-Care Inventory (SCI).
One-hundred and five youth with T1D self-reported their T1D engagement using the SCI. We also collected two weeks of insulin pump data and a concurrent HbA1c level. We scored youth's SCI and calculated their mean insulin BOLUS score using standardized methods. For the analyses, we performed simple correlations, partial correlations, and multiple regression models.
Youth had a mean age of 15.03 ± 1.97 years, mean time since diagnosis of 8.11 ± 3.26 years, and a mean HbA1c of 8.78 ± 1.49%. The sample included n = 58 boys (55%) and n = 96 families (91%) self-identified as white. Simple correlations between youth's age, HbA1c, SCI total score, and BOLUS score were all significant. Partial correlation and regression models revealed that youth's insulin BOLUS score was more strongly associated with HbA1c than the SCI.
Youths' BOLUS score has better concurrent validity with HbA1c than the SCI. We should consider reporting the BOLUS score as an outcome metric in insulin pump data reports.
为了达到糖化血红蛋白(HbA1c)目标,1型糖尿病(T1D)青少年需要参与其日常的T1D治疗。餐时胰岛素大剂量评分(BOLUS)是衡量青少年T1D参与度的客观指标,我们之前已证明,在预测青少年的HbA1c方面,该指标优于其他客观参与度指标。在此,为了进一步评估BOLUS评分的有效性,我们比较了青少年HbA1c与其平均胰岛素BOLUS评分以及一种有效的T1D参与度自我报告指标——自我护理量表(SCI)之间关联的强度。
105名T1D青少年使用SCI自我报告了他们的T1D参与度。我们还收集了两周的胰岛素泵数据以及同期的HbA1c水平。我们对青少年的SCI进行评分,并使用标准化方法计算他们的平均胰岛素BOLUS评分。对于分析,我们进行了简单相关性分析、偏相关性分析和多元回归模型分析。
青少年的平均年龄为15.03±1.97岁,平均确诊时间为8.11±3.26年,平均HbA1c为8.78±1.49%。样本包括n = 58名男孩(55%)和n = 96个家庭(91%)自认为是白人。青少年的年龄、HbA1c、SCI总分和BOLUS评分之间的简单相关性均显著。偏相关性和回归模型显示,青少年的胰岛素BOLUS评分与HbA1c的关联比SCI更强。
青少年的BOLUS评分与HbA1c的同时效度优于SCI。我们应考虑在胰岛素泵数据报告中,将BOLUS评分作为一项结果指标进行报告。