BION Institute, Stegne 21, 1000 Ljubljana, Slovenia.
Int J Mol Sci. 2023 Jul 26;24(15):11961. doi: 10.3390/ijms241511961.
Physicochemical investigations of (UHD) solutions subjected to certain physical factors (like shaking) are becoming more frequent and increasingly yielding convincing results. A much less studied phenomenon is the transfer of molecular information (UHD signals) from one fluid to another without an intermediate liquid phase. The purpose of this study was to investigate the possibility of such a UHD signal transfer from UHD solutions into the receiver fluid, especially when the molecular source used in solutions was a biologically active molecule of antibodies to interferon-gamma. We used physicochemical measurements and UV spectroscopy for this purpose. The results of this large pilot study confirm the possibility of such a transfer and a rough similarity to the original UHD signal donors, the weaker signal detection relative to the original donor fluids, and that exposure time improves the effect.
（UHD）溶液在某些物理因素（如摇晃）下的物理化学研究变得越来越频繁，并且越来越多地产生令人信服的结果。一个研究得较少的现象是分子信息（UHD 信号）从一种流体传递到另一种流体而无需中间液相。本研究的目的是研究这种 UHD 信号是否可以从 UHD 溶液传递到接收液中，特别是当溶液中使用的分子源是生物活性分子干扰素-γ的抗体。为此，我们使用了物理化学测量和紫外光谱。这项大型初步研究的结果证实了这种传递的可能性，并且与原始 UHD 信号供体具有大致相似性，与原始供体流体相比，信号检测较弱，并且暴露时间可以提高效果。
