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用于递送核酸纳米结构的介孔二氧化硅纳米颗粒的合成

Synthesis of Mesoporous Silica Nanoparticles for the Delivery of Nucleic Acid Nanostructures.

作者信息

Huq Tamanna Binte, Vivero-Escoto Juan L

机构信息

Department of Chemistry, Nanoscale Science Program, University of North Carolina, Charlotte, NC, USA.

出版信息

Methods Mol Biol. 2023;2709:205-210. doi: 10.1007/978-1-0716-3417-2_13.

Abstract

Nanomaterials have been extensively used for the delivery of nucleic acids. This is attributed to the unique features of nanoparticles to carry genetic material with different physiochemical properties. Mesoporous silica nanoparticles (MSNPs) are a versatile platform for the efficient delivery of nuclei acid-based materials. In this chapter, we describe the synthesis of MSNPs to efficiently transport nucleic acid nanoparticles.

摘要

纳米材料已被广泛用于核酸递送。这归因于纳米颗粒携带具有不同物理化学性质的遗传物质的独特特性。介孔二氧化硅纳米颗粒(MSNPs)是高效递送核酸类材料的通用平台。在本章中,我们描述了用于有效运输核酸纳米颗粒的MSNPs的合成方法。

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