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胸腹腔镜手术中椎旁与硬膜外麻醉的比较:一项随机试验。

Paravertebral vs Epidural Anesthesia for Video-assisted Thoracoscopic Surgery: A Randomized Trial.

机构信息

Department of Thoracic Surgery, the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Department of Medical Quality Management, the Women's Hospital, Zhejiang University School of Medicine, Hangzhou, China.

出版信息

Ann Thorac Surg. 2023 Nov;116(5):1006-1012. doi: 10.1016/j.athoracsur.2023.07.038. Epub 2023 Aug 12.

Abstract

BACKGROUND

The choice of postoperative pain management for patients who experience moderate to severe acute pain after thoracoscopic surgery is debatable. This study aimed to determine whether paravertebral block (PVB) provides more benefits than thoracic epidural analgesia (TEA) for thoracoscopic surgery.

METHODS

From February 2020 to April 2022, patients without chronic pain who were scheduled to undergo thoracoscopic surgery were randomly assigned to the PVB group or the TEA group. The visual analogue scale score was used to measure the degree of pain when the patients were at rest or coughing.

RESULTS

In total, 176 eligible patients were enrolled in this study. No significant difference in the visual analogue scale score was found between the 2 groups at rest (P = .395) or with coughing (P = .157). Additionally, there was no significant difference in the average pain score between these 2 states (P = .221). The median time for catheter placement in the PVB group was 5 minutes, which was shorter than that (14 minutes) in the TEA group (P < .001). Moreover, the catheter placement failure rate in the PVB group was lower than that in the TEA group (P = .038). The incidence of hypotension (P = .016) and urinary retention (P = .006) in the PVB group was lower than that in the TEA group.

CONCLUSIONS

PVB can provide pain relief that is similar to that of TEA but with no additional puncture pain, a shorter catheter placement time, and fewer side effects in patients undergoing video-assisted thoracoscopic surgery.

摘要

背景

对于接受胸腔镜手术后出现中重度急性疼痛的患者,术后疼痛管理方式的选择存在争议。本研究旨在确定椎旁阻滞(PVB)是否比胸段硬膜外镇痛(TEA)更有益于胸腔镜手术。

方法

本研究纳入了 2020 年 2 月至 2022 年 4 月期间无慢性疼痛且拟行胸腔镜手术的患者,他们被随机分配到 PVB 组或 TEA 组。使用视觉模拟评分法(VAS)来衡量患者在休息或咳嗽时的疼痛程度。

结果

本研究共纳入了 176 例符合条件的患者。两组患者在休息时(P =.395)或咳嗽时(P =.157)的 VAS 评分均无显著差异。此外,这两种状态下的平均疼痛评分也无显著差异(P =.221)。PVB 组的导管放置中位时间为 5 分钟,短于 TEA 组的 14 分钟(P <.001)。此外,PVB 组的导管放置失败率也低于 TEA 组(P =.038)。PVB 组低血压(P =.016)和尿潴留(P =.006)的发生率低于 TEA 组。

结论

与 TEA 相比,PVB 可为行电视辅助胸腔镜手术的患者提供相似的镇痛效果,但不会增加穿刺疼痛,导管放置时间更短,且副作用更少。

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