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获得性免疫缺陷综合征非海地患者中的结核病

Tuberculosis in non-Haitian patients with acquired immunodeficiency syndrome.

作者信息

Louie E, Rice L B, Holzman R S

出版信息

Chest. 1986 Oct;90(4):542-5. doi: 10.1378/chest.90.4.542.

Abstract

From Jan 1, 1981 to Oct 31, 1984, 24 of 280 (8.6 percent) patients with acquired immunodeficiency syndrome (AIDS) had tuberculosis. No patient with both AIDS and tuberculosis was Haitian. In 15 patients, tuberculosis was diagnosed prior to or concomitant with the diagnosis of AIDS. Twelve patients (50 percent) had Mycobacterium tuberculosis grown from at least one extrapulmonary site. Although the clinical presentation was variable, no patient had cavitary and only one had apical disease. Histologic examination of lung and transbronchial biopsy specimens usually did not reveal acid-fast bacilli or granulomas. Seventeen patients were treated and all showed clinical improvement. Tuberculosis was infrequent but not rare in our patients and often preceded the diagnosis of AIDS. Despite the fact that many of these patients had both severe and extrapulmonary disease, they appeared to respond well to treatment.

摘要

1981年1月1日至1984年10月31日期间,280例获得性免疫缺陷综合征(AIDS)患者中有24例(8.6%)患结核病。同时患有AIDS和结核病的患者中没有海地人。15例患者在诊断AIDS之前或同时被诊断出患有结核病。12例患者(50%)至少有一个肺外部位培养出结核分枝杆菌。尽管临床表现各异,但没有患者有空洞形成,只有1例有肺尖部病变。肺组织学检查和经支气管活检标本通常未发现抗酸杆菌或肉芽肿。17例患者接受了治疗,所有患者临床症状均有改善。结核病在我们的患者中并不常见但也不罕见,且常先于AIDS的诊断出现。尽管这些患者中有许多患有严重的肺外疾病,但他们似乎对治疗反应良好。

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