Davis Alissa, Mergenova Gaukhar, Landers Sara E, Sun Yihang, Rozental Elena, Gulyaev Valera, Gulyaev Pavel, Nurkatova Mira, Terlikbayeva Assel, Primbetova Sholpan, Altice Frederick L, Remien Robert H
School of Social Work, Columbia University, New York, United States.
Global Health Research Center of Central Asia, Almaty, Kazakhstan.
Res Soc Work Pract. 2023 Mar;33(3):313-324. doi: 10.1177/10497315221117543. Epub 2022 Aug 11.
HIV-positive people who inject drugs (PWID) in Kazakhstan face many challenges to antiretroviral therapy (ART) adherence. Interventions that leverage social support from an intimate partner, family member, or friend may be effective in improving ART adherence among this population. The purpose of this paper is to describe the implementation process of a dyad-based intervention among HIV-positive PWID and their treatment support partners.
Sixty-six HIV-positive PWID and 66 of their treatment support partners will be enrolled in this pilot randomized controlled trial in Almaty, Kazakhstan, and randomized as dyads to receive an adapted version of the SMART Couples intervention or standard of care.
Several implementation strategies were used to facilitate intervention delivery, including remote delivery, training of staff, supervision, technical assistance, quality assurance, and collection of assessments through diverse sources.
This trial responds to a need for dyad-based ART adherence interventions adapted specifically for HIV-positive PWID.
哈萨克斯坦注射毒品的艾滋病毒阳性者（PWID）在坚持抗逆转录病毒治疗（ART）方面面临诸多挑战。利用亲密伴侣、家庭成员或朋友提供的社会支持的干预措施可能有助于提高这一人群的ART依从性。本文旨在描述针对艾滋病毒阳性PWID及其治疗支持伙伴开展的基于二元组的干预措施的实施过程。
66名艾滋病毒阳性PWID及其66名治疗支持伙伴将参与哈萨克斯坦阿拉木图的这项试点随机对照试验，并作为二元组随机分组，接受改良版的SMART夫妻干预措施或标准护理。
采用了多种实施策略来促进干预措施的实施，包括远程实施、工作人员培训、监督、技术援助、质量保证以及通过多种来源收集评估数据。
该试验满足了针对艾滋病毒阳性PWID专门制定基于二元组的ART依从性干预措施的需求。
