Weise F, Müller D, Krell D, Kielstein V, Koch R D
Drug Alcohol Depend. 1986 Jul;17(4):365-8. doi: 10.1016/0376-8716(86)90086-4.
Heart rate variability (HRV) was studied in 11 chronic alcoholic subjects, 1-30 days after the beginning of abstinence and again 5, 12 and 24 weeks later. Two patients could be re-examined after 19 and 22 months, respectively. In the follow-up study, the total patient group showed a statistically significant increase in HRV with prolonged abstinence of at least 6 months. No recovery of efferent vagal function was found in 4 patients. It is suggested that the vagal neuropathy may improve in chronic alcoholics, but perhaps only in patients with a short to moderately long duration of drinking history or a functional rather than an organic vagal damage.
对11名慢性酒精中毒患者进行了心率变异性（HRV）研究，分别在戒酒开始后的1至30天以及5周、12周和24周后进行再次检测。两名患者分别在19个月和22个月后接受了复查。在后续研究中，整个患者组显示，随着至少6个月的长期戒酒，HRV有统计学意义的增加。4名患者未发现传出迷走神经功能恢复。研究表明，慢性酒精中毒患者的迷走神经病变可能会改善，但可能仅见于饮酒史较短至中等时长或功能性而非器质性迷走神经损伤的患者。
