癫痫发作后2个月，杏仁核点燃大鼠脑区中去甲肾上腺素周转率和浓度未发生变化。

Unchanged norepinephrine turnover and concentrations in amygdala-kindled rat brain regions 2 months postseizure.

作者信息

Okazaki M M, Warsh J J, Burnham W M

出版信息

Exp Neurol. 1986 Oct;94(1):81-90. doi: 10.1016/0014-4886(86)90273-6.

Abstract

Norepinephrine turnover and concentrations were examined in eight brain regions of amygdala-kindled and yoked control rats. The subjects were killed 2 months after the kindled subjects had exhibited their sixth "stage 4-5" generalized seizure. No significant differences were found in norepinephrine turnover or concentrations between kindled and yoked control rats in any of the brain regions examined. Dopamine turnover and concentrations in brain regions were also unchanged in kindled rats compared with their yoked controls. The data suggest that amygdala kindling does not produce any long-lasting alterations in brain regional catecholamine turnover or concentrations.

摘要

对杏仁核点燃大鼠和配对对照大鼠的八个脑区的去甲肾上腺素周转率和浓度进行了检测。在点燃大鼠出现第六次“4 - 5期”全身性癫痫发作2个月后将实验对象处死。在所检测的任何脑区中，点燃大鼠和配对对照大鼠的去甲肾上腺素周转率或浓度均未发现显著差异。与配对对照大鼠相比，点燃大鼠脑区的多巴胺周转率和浓度也未发生变化。数据表明，杏仁核点燃不会在脑区儿茶酚胺周转率或浓度上产生任何持久的改变。