Song Feng, Xie Yang, Guo Nannan, Zhao Hulei
Collaborative Innovation Center for Respiratory Disease Diagnosis and Treatment & Chinese Medicine Development of Henan Province, Henan University of Chinese Medicine, Henan, China.
Henan Key Laboratory of Chinese Medicine for Respiratory Disease, Henan University of Chinese Medicine, Henan, China.
Arch Public Health. 2023 Aug 16;81(1):147. doi: 10.1186/s13690-023-01162-8.
Some reports demonstrate that asthma benefits from milk and dairy products, however, the findings are controversial. We used meta-analysis as a tool to summarize published data on the association between dairy products consumption and asthma.
A systematic literature search was conducted to identify studies of dairy products and asthma in children in PubMed, ISI (Web of Science), and EMBASE until 21 July 2022. Random-effect meta-analyses with summarized data were performed for total (high/low) milk and dairy intake. Subgroup analysis was used to identify sources of variation in responses. Publication bias and sensitivity analysis were done to examine the stability of results.
There was no correlation between consumption of dairy products and reduced risk of asthma (OR = 0.82; 95% CI: 0.60-1.05). Our results revealed that elevated consumption of milk and dairy has significant correlation with reduced risk of asthma in Non-Asian population (OR = 0.74; 95% CI = 0.51-0.96) and high quality studies (OR = 0.73; 95% CI = 0.50-0.95). No individual study influence and publication bias was seen in the sensitivity analysis and publication bias assessment.
There was no correlation between consumption of dairy products and reduced risk of asthma. However, we observed that elevated consumption of milk and dairy has significant correlation with reduced risk of asthma in Non-Asian population and high quality studies. More high-quality and population-specific studies should be conducted to determine the risk link between milk consumption and asthma in children.
一些报告表明哮喘患者可从牛奶及乳制品中获益，然而，研究结果存在争议。我们使用荟萃分析作为工具来总结已发表的关于乳制品消费与哮喘之间关联的数据。
进行了系统的文献检索，以确定截至2022年7月21日在PubMed、ISI（科学网）和EMBASE中有关儿童乳制品与哮喘的研究。对总（高/低）牛奶及乳制品摄入量进行了汇总数据的随机效应荟萃分析。采用亚组分析来确定反应差异的来源。进行了发表偏倚和敏感性分析以检验结果的稳定性。
乳制品消费与哮喘风险降低之间无相关性（OR = 0.82；95% CI：0.60 - 1.05）。我们的结果显示，在非亚洲人群（OR = 0.74；95% CI = 0.51 - 0.96）和高质量研究（OR = 0.73；95% CI = 0.50 - 0.95）中，牛奶及乳制品摄入量增加与哮喘风险降低显著相关。在敏感性分析和发表偏倚评估中未发现个别研究的影响和发表偏倚。
乳制品消费与哮喘风险降低之间无相关性。然而，我们观察到在非亚洲人群和高质量研究中，牛奶及乳制品摄入量增加与哮喘风险降低显著相关。应开展更多高质量且针对特定人群的研究，以确定儿童牛奶消费与哮喘之间的风险联系。
